Genome-wide Off-target Cleavage Prediction of CRISPR/Cas Nucleases

Title

Genome-wide Off-target Cleavage Prediction of CRISPR/Cas Nucleases

 Author

de Jong, Sonny Floyd (TU Delft Applied Sciences)

Contributor

Klein, M. (mentor)
Depken, S.M. (mentor) ORCID 0000-0001-9194-6739
Idema, T. (graduation committee) ORCID 0000-0002-8901-5342

 Degree granting institution

Delft University of Technology
Erasmus Universiteit Rotterdam

 Programme

Applied Sciences | Nanobiology

 Date

2020-02-03

 Abstract

Predicting off-target cleavage sites for CRISPR/Cas nucleases on the human genome based on biophysical modelling and high-throughput biochemical profiling.

 Subject

CRISPR-Cas
Off-targetting
Biophysical model
Gene therapy

 To reference this document use:

http://resolver.tudelft.nl/uuid:a1f0dd58-4d3a-4814-b41a-531fc1a432e4

 Part of collection

Student theses

 Document type

bachelor thesis

 Rights

© 2020 Sonny Floyd de Jong
Files
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