Print Email Facebook Twitter Protein stabilisation and controlled particulate production by supercritical fluid drying Title Protein stabilisation and controlled particulate production by supercritical fluid drying Author Bouchard, A.M.J.L. Contributor Witkamp, G.J. (promotor) Crommelin, D.J.A. (promotor) Jiskoot, W. (promotor) Faculty Mechanical Maritime and Materials Engineering Date 2007-05-29 Abstract Carbon dioxide was used as a drying medium for the preparation of micro-size powders from aqueous solutions in a high-pressure spray-drying process. This technology was shown to be an alternative to traditional drying processes that could be successfully used for the dry formulation of therapeutic proteins, the preparation of stable amorphous products, the selective production of polymorphs and pseudomorphs, and the design of particles. Subject supercriticalcarbon dioxideaqueousproteinsugarpolyolspolysaccharidesamino acidsamorphouspolymorphpseudomorph To reference this document use: http://resolver.tudelft.nl/uuid:d609aa4b-56fc-48b4-ab4e-83cb22009b89 ISBN 978-90-9021893-9 Part of collection Institutional Repository Document type doctoral thesis Rights (c) 2007 A.M.J.L. Bouchard Files PDF 3me_bouchard_20070529.pdf 13.68 MB Close viewer /islandora/object/uuid:d609aa4b-56fc-48b4-ab4e-83cb22009b89/datastream/OBJ/view