Heat induced attachment and detachment of delicate tissues: Towards a new micro tissue gripper

Heat induced attachment and detachment of delicate tissues: Towards a new micro tissue gripper

Tukker, A.A.

Dankelman, J. (mentor)
Van Meurs, J.C. (mentor)

Mechanical, Maritime and Materials Engineering

BioMechanical Engineering

BioMedical Engineering: Medical Instruments & Medical Safety

2010-03-24

Indirect Heat Induced Attachment and Detachment (HIAD) is a promising concept for gripping delicate tissues in ophthalmic surgery. However, the optimal settings of attaching to and detaching from delicate tissues are unknown. This study presents the effects of the instrument heating properties and initial contact force on the adhesion force, detachment success and thermal damage. An instrument prototype was developed to test attachment and detachment for different combinations of generated heat (3.5-20.0mJ) and pulse length (0.25-2.50ms). Thermal tissue damage was estimated with electro-thermal FEM simulations and histological analysis. The adhesion force depended strongly on the amount of generated heat and contact force. Pulse length played a minor role. Detachment success was determined by the maximum instrument temperature. Thermal tissue damage was strongly related to the amount of generated heat, the effect of pulse length was marginal. In RPE-choroid graft analysis, the RPE cells were not affected by heat. HIAD proved sensitive to heating characteristics and tissue properties. Nevertheless, this principle creates potential to build better performing tissue manipulators.

heat
tissue
adhesion
detachment
damage
eye

http://resolver.tudelft.nl/uuid:71d08db8-0b11-477c-a006-75348bc82e83

2011-07-01

Student theses

master thesis

(c) 2010 Tukker, A.A.