Print Email Facebook Twitter Convergence behavior of single-step GBLUP and SNPBLUP for different termination criteria Title Convergence behavior of single-step GBLUP and SNPBLUP for different termination criteria Author Vandenplas, Jérémie (Wageningen University & Research) Calus, Mario P.L. (Wageningen University & Research) Eding, Herwin (CRV BV) van Pelt, Mathijs (CRV BV) Bergsma, Rob (Topigs Norsvin) Vuik, Cornelis (TU Delft Numerical Analysis) Date 2021 Abstract BackgroundThe preconditioned conjugate gradient (PCG) method is the current method of choice for iterative solving of genetic evaluations. The relative difference between two successive iterates and the relative residual of the system of equations are usually chosen as a termination criterion for the PCG method in animal breeding. However, our initial analyses showed that these two commonly used termination criteria may report that a PCG method applied to a single-step single nucleotide polymorphism best linear unbiased prediction (ssSNPBLUP) is not converged yet, whereas the solutions are accurate enough for practical use. Therefore, the aim of this study was to propose two termination criteria that have been (partly) developed in other fields, but are new in animal breeding, and to compare their behavior to that of the two termination criteria widely used in animal breeding for the PCG method applied to ssSNPBLUP. The convergence patterns of ssSNPBLUP were also compared to the convergence patterns of single-step genomic BLUP (ssGBLUP).ResultsBuilding upon previous work, we propose two termination criteria that take the properties of the system of equations into account. These two termination criteria are directly related to the relative error of the iterates with respect to the true solutions. Based on pig and dairy cattle datasets, we show that the preconditioned coefficient matrices of ssSNPBLUP and ssGBLUP have similar properties when using a second-level preconditioner for ssSNPBLUP. Therefore, the PCG method applied to ssSNPBLUP and ssGBLUP converged similarly based on the relative error of the iterates with respect to the true solutions. This similar convergence behavior between ssSNPBLUP and ssGBLUP was observed for both proposed termination criteria. This was, however, not the case for the termination criterion defined as the relative residual when applied to the dairy cattle evaluations.ConclusionOur results showed that the PCG method can converge similarly when applied to ssSNPBLUP and to ssGBLUP. The two proposed termination criteria always depicted these similar convergence behaviors, and we recommend them for comparing convergence properties of different models and for routine evaluations. To reference this document use: http://resolver.tudelft.nl/uuid:7ce279bb-d660-4255-93d9-29fbbbe316b2 DOI https://doi.org/10.1186/s12711-021-00626-1 ISSN 1297-9686 Source Genetics Selection Evolution, 53 (1), 1-15 Part of collection Institutional Repository Document type journal article Rights © 2021 Jérémie Vandenplas, Mario P.L. Calus, Herwin Eding, Mathijs van Pelt, Rob Bergsma, Cornelis Vuik Files PDF s12711_021_00626_1.pdf 2.16 MB Close viewer /islandora/object/uuid:7ce279bb-d660-4255-93d9-29fbbbe316b2/datastream/OBJ/view