Print Email Facebook Twitter Hyperpolarised gas filling station for medical imaging using polarised 129Xe and 3He Title Hyperpolarised gas filling station for medical imaging using polarised 129Xe and 3He Author Lee, Wai Tung (Australia Nuclear Science and Technology Organization, New South Wales 2234) Zheng, Gang (Monash University) Talbot, Cavin L. (University of Queensland) Tong, Xin (Institute of High Energy Physics Chinese Academy of Science; Spallation Neutron Source Science Center, Dongguan) D'Adam, Tim (Australia Nuclear Science and Technology Organization, New South Wales 2234) Parnell, S.R. (TU Delft RID/TS/Instrumenten groep) de Veer, Michael (Monash University) Jenkin, Graham (Monash University and Hudson Institute of Medical Research) Polglase, Graeme R. (Monash University and Hudson Institute of Medical Research; Monash University) Date 2021 Abstract We report the design, construction, and initial tests of a hyperpolariser to produce polarised 129Xe and 3He gas for medical imaging of the lung. The hyperpolariser uses the Spin-Exchange Optical Pumping method to polarise the nuclear spins of the isotopic gas. Batch mode operation was chosen for the design to produce polarised 129Xe and polarised 3He. Two-side pumping, electrical heating and a piston to transfer the polarised gas were some of the implemented techniques that are not commonly used in hyperpolariser designs. We have carried out magnetic resonance imaging experiments demonstrating that the 3He and 129Xe polarisation reached were sufficient for imaging, in particular for in vivo lung imaging using 129Xe. Further improvements to the hyperpolariser have also been discussed. Subject Hyperpolarised Helium-3Hyperpolarised Xenon-129HyperpolariserMRI lung imaging: Spin-exchange optical pumping To reference this document use: http://resolver.tudelft.nl/uuid:808c06e5-549d-467f-8066-d2d6d5e553f3 DOI https://doi.org/10.1016/j.mri.2021.02.010 Embargo date 2022-03-26 ISSN 0730-725X Source Magnetic Resonance Imaging, 79, 112-120 Bibliographical note Accepted Author Manuscript Part of collection Institutional Repository Document type journal article Rights © 2021 Wai Tung Lee, Gang Zheng, Cavin L. Talbot, Xin Tong, Tim D'Adam, S.R. Parnell, Michael de Veer, Graham Jenkin, Graeme R. Polglase, More Authors Files PDF Lee_2021_Hyperpolarised_G ... nd_3He.pdf 825.8 KB Close viewer /islandora/object/uuid:808c06e5-549d-467f-8066-d2d6d5e553f3/datastream/OBJ/view