Print Email Facebook Twitter Advances in the development of a novel method to be used in proteomics using gold nanobeads Title Advances in the development of a novel method to be used in proteomics using gold nanobeads Author Dietrich, H.R.C. Young, I.T. Garini, Y. Faculty Applied Sciences Department Quantitative Imaging Group Date 2006-02-27 Abstract The study of DNA-protein interactions is gaining increased attention due to their importance in cellular processes. Only a well-functioning interaction guaranties that such a process can take place without errors. So far, only a small percentage of these interactions have been unraveled, partially due to their complexity but also due to the fact that there are only a few techniques that permit the study of these interactions. In this report we describe the development of a research tool based on tethered bead motion and Resonance Light Scattering (RLS) from gold beads. This method permits the study of DNA-protein interactions and the screening of proteins binding to a specific DNA sequence. Subject single molecule detectionresonance light scatteringmolecular interactionsquantitative microscopy To reference this document use: http://resolver.tudelft.nl/uuid:84ac9982-f1d3-4171-b55f-bb9fb0795ac7 Publisher SPIE ISSN 0277-786X Source Proceedings of SPIE, 2006 vol. 6092 Part of collection Institutional Repository Document type conference paper Rights (c)2006 Dietrich, H.R.C., Young, I.T., Garini, Y. Files PDF AdvancesHeidelinde.pdf 1.07 MB Close viewer /islandora/object/uuid:84ac9982-f1d3-4171-b55f-bb9fb0795ac7/datastream/OBJ/view