Print Email Facebook Twitter Synthesis of enantiomerically pure alcohols and amines Title Synthesis of enantiomerically pure alcohols and amines: Via biocatalytic deracemisation methods Author Musa, Musa M. (King Fahd University of Petroleum and Minerals) Hollmann, F. (TU Delft BT/Biocatalysis) Mutti, Francesco G. (Universiteit van Amsterdam) Date 2019 Abstract Deracemisation via chemo-enzymatic or multi-enzymatic approaches is the optimum substitute for kinetic resolution, which suffers from the limitation of a theoretical maximum 50% yield albeit high enantiomeric excess is attainable. This review covers the recent progress in various deracemisation approaches applied to the synthesis of enantiomerically pure alcohols and amines, such as (1) dynamic kinetic resolution, (2) cyclic deracemisation, (3) linear deracemisation (including stereoinversion) and (4) enantioconvergent methods. To reference this document use: http://resolver.tudelft.nl/uuid:c9d29ae9-e82c-4fae-a47d-ef4f0f81efca DOI https://doi.org/10.1039/c9cy01539f ISSN 2044-4753 Source Catalysis Science & Technology, 9 (20), 5487-5503 Part of collection Institutional Repository Document type review Rights © 2019 Musa M. Musa, F. Hollmann, Francesco G. Mutti Files PDF c9cy01539f.pdf 4.1 MB Close viewer /islandora/object/uuid:c9d29ae9-e82c-4fae-a47d-ef4f0f81efca/datastream/OBJ/view