A method for finding metabolic pathways using atomic group tracking

A fundamental computational problem in metabolic engineering is to find pathways between compounds. Pathfinding methods using atom tracking have been widely used to find biochemically relevant pathways. However, these methods require the user to define the atoms to be tracked. This may lead to failing to predict the pathways that do not...

Spectroscopic evidence for bulk-band inversion and three-dimensional massive Dirac fermions in ZrTe₅

Three-dimensional topological insulators (3D TIs) represent states of quantum matters in which surface states are protected by timereversal symmetry and an inversion occurs between bulk conduction and valence bands. However, the bulk-band inversion, which is intimately tied to the topologically nontrivial nature of 3D Tis, has rarely been...

The influence of statistical uncertainty in the hydraulic boundary conditions on the probabilistically computed highwater level frequency curve in the Rhine Delta

The hydrodynamic characteristics of a delta or estuary are mainly governed by discharges of rivers and water level at the sea (or lake) boundaries. A joint probability approach is widely applied to quantify the high water level frequency in deltas. In the approach the relevant hydrodynamic loading variables, namely the astronomical tides, the...