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van Gemert, Y. (author), Kozijn, A. E. (author), Pouwer, M. G. (author), Kruisbergen, N. N.L. (author), van den Bosch, M. H.J. (author), Blom, A.B. (author), Pieterman, E. J. (author), Weinans, Harrie (author), Stoop, R. (author), Princen, H. M.G. (author), van Lent, P. L.E.M. (author)Objective: High systemic cholesterol levels have been associated with osteoarthritis (OA) development. Therefore, cholesterol lowering by statins has been suggested as a potential treatment for OA. We investigated whether therapeutic high-intensive cholesterol-lowering attenuated OA development in dyslipidemic APOE∗3Leiden.CETP mice. Methods:...journal article 2021
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Andrikopoulou, T. (author), Schielen, R.M.J. (author), Spray, Chris J. (author), Schipper, Cor A. (author), Blom, A. (author)Nature-based solutions (NBSs) are measures reflecting the ‘cooperation with nature’ approach: mitigating fluvial flood risk while being cost-effective, resource-efficient, and providing numerous environmental, social, and economic benefits. Since 2015, the United Nations (UN) 2030 Agenda has provided UN member states with goals, targets, and...journal article 2021
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Zeng, X. (author), Blom, A. (author), Czapiga, Matthew J. (author), An, Chenge (author), Parker, Gary (author), Fu, Xudong (author)For upland ephemeral gullies, gully erosion is strongly related to the formation and migration of cyclic steps. It is necessary to provide insight into the process of cyclic step development to accurately predict the pace of landscape evolution and soil loss. Information on the geometry of cyclic steps in subaerial environments is limited,...journal article 2021
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Arkesteijn, L. (author), Blom, A. (author), Labeur, R.J. (author)Recent analysis of equilibrium and quasi-equilibrium channel geometry in engineered (fixed-width) rivers has successfully shown that two temporal scales can be distinguished, with quasi-static (long-term) and dynamic (short-term) components. This distinction is based on the fact that channel slope cannot keep pace with short-term fluctuations...journal article 2021
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Jansen, J.D. (author), Blom, J.C. (author), Free, Renske (author), Kouwenhoven, Paula (author), Fokkema, J.T. (author), de Bruijn, Birgit (author), Smeulders, Julien (author), Drenth, D.J.H. (author), van der Kleijn, Piet Hein (author)This booklet provides additional information to the work of art 'Soft Layer' located in front of the faculty of Civil Engineering and Geosciences. This piece of art is an initiative of students and alumni of the Mijnbouwkundige Vereeniging and has been revealed on the 24th of February, 2020.other 2020
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van de Vyver, Ighor (author), Harvey-Scholes, Calum (author), Hoggett, Richard (author), Hoppe, T. (author), Jansen, S.C. (author), Fremouw, M.A. (author), Blom, Tess (author), Itten, A.V. (author), Pauvert, Alexandre (author)SHIFFT is an Interreg 2 Seas project, running from 2019-2022, promoting cross-border cooperation between 4 European countries: The Netherlands, France, Belgium and The United Kingdom. It has been approved under the priority ‘Low Carbon Technologies’.report 2020
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Abate, Alessandro (author), Blom, H.A.P. (author), Cauchi, Nathalie (author), Delicaris, Joanna (author), Hartmanns, Arnd (author), Khaled, Mahmoud (author), Lavaei, Abolfazl (author), Pilch, Carina (author), Remke, Anne (author)This report presents the results of a friendly competition for formal verification and<br/>policy synthesis of stochastic models. It also introduces new benchmarks within this<br/>category, and recommends next steps for this category towards next year's edition of the competition. The friendly competition took place as part of the workshop...conference paper 2020
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Ylla Arbos, C. (author), Blom, A. (author), Acevedo Goldaracena, F. (author), van Vuren, S (author), Schielen, R.M.J. (author)The Rhine reach comprising the Niederrhein and the Upper Rhine Delta is characterized by a long history of engineering interventions. The area is densely populated and the Rhine, the main inland waterway in Europe, justifying the need for such measures. Interventions have had a strong impact on morphodynamic channel characteristics. We use bed...conference paper 2020
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Hunink, Yvo Thomas Anton (author), Kamp, L.M. (author), Blom, E.M. (author)Energy system projects in countries like India are often failing. Not only because of technical or economical barriers, but mainly institutional and social issues are at the base of these failures. A co-creation, or participatory, process to align all demands and requirements of the different stakeholders is required. This paper takes...conference paper 2020
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Rattanagraikanakorn, B. (author), Blom, H.A.P. (author), Sharpanskykh, Alexei (author), de Wagter, C. (author), Jiang, C. (author), Schuurman, M.J. (author), Gransden, Derek I. (author), Happee, R. (author)Evaluating safety risk posed to third parties on the ground due to UAS impact requires a model of probability of fatality (PoF) for human. For quadrotor UAS, the existing impact models predict remarkably different PoFs. The most pessimistic is the impact model adopted by Range Commanders Council (RCC) while the Blunt Criterion model is far...conference paper 2020
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Jiang, C. (author), Blom, H.A.P. (author), Sharpanskykh, Alexei (author)Use of Unmanned Aircraft Systems (UAS) is growing rapidly around the world. Very different types of UAS are used for applications such as aerial photography, inspection, emergency and Urban Air Mobility (UAM), operating in low altitude and urban environment, as well as in high altitude airspace integrated with the conventional air transportation...conference paper 2020
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Rattanagraikanakorn, B. (author), Schuurman, M.J. (author), Gransden, Derek I. (author), Happee, R. (author), de Wagter, C. (author), Sharpanskykh, Alexei (author), Blom, H.A.P. (author)Recent developments in the concept of UAS operations in urban areas have led to risk concerns of UAS collision with human. To better understand this risk, head and neck injuries due to UAS collisions have been investigated by different research teams using crash dummies. Because of the limitations in biofidelity of a crash dummy, head injury...journal article 2020
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Stroeve, Sybert H. (author), Blom, H.A.P. (author), Medel, Carlos Hernandez (author), Daroca, Carlos Garcia (author), Cebeira, Alvaro Arroyo (author), Drozdowski, Stanislaw (author)Airborne collision avoidance systems (ACASs) form a key safety barrier by providing last-moment resolution advisories (RAs) to pilots for avoiding midair collisions. Intrinsic uncertainties, such as noise in ACAS input signals and variability in pilot performance, imply that the generation of RAs and the effectuated aircraft trajectories are...journal article 2020
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Bongaerts, Michiel (author), Bonte, Ramon (author), Demirdas, Serwet (author), Jacobs, Edwin H. (author), Oussoren, Esmee (author), van der Ploeg, Ans T. (author), Wagenmakers, Margreet A.E.M. (author), Hofstra, Robert M.W. (author), Blom, Henk J. (author), Reinders, M.J.T. (author), Ruijter, George J.G. (author)Untargeted metabolomics is an emerging technology in the laboratory diagnosis of inborn errors of metabolism (IEM). Analysis of a large number of reference samples is crucial for correcting variations in metabolite concentrations that result from factors, such as diet, age, and gender in order to judge whether metabolite levels are abnormal....journal article 2020
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Sun, Junzi (author), Blom, H.A.P. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)This article investigates the estimation of aircraft mass and thrust settings of departing aircraft using a recursive Bayesian method called particle filtering. The method is based on a nonlinear state-space system derived from aircraft point-mass performance models. Using only aircraft surveillance data, flight states such as position,...journal article 2019
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Chen, B. (author), Sun, Yubo (author), Jacquemin, Loic (author), Zhang, Shizhe (author), Blom, Kees (author), Lukovic, M. (author), Ye, G. (author)At present, most municipal solid waste incineration (MSWI) bottom ash, as being disposed of as waste, is directly landfilled, raising concern about the environmental issue and potential loss of resources. Given that the natural raw materials used for cement production are being depleted, the recycling of MSWI bottom ash for the application as...conference paper 2019
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Chavarrias Borras, V. (author), Stecca, Guglielmo (author), Siviglia, Annunziato (author), Blom, A. (author)A notable drawback in mixed-size sediment morphodynamic modeling is the fact that the most commonly used mathematical model in this field (i.e., the active layer model Hirano, 1971) can be ill-posed under certain circumstances. Under these conditions the model loses its predictive capabilities, as negligible perturbations in the initial or...journal article 2019
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Chavarrias Borras, V. (author), Schielen, R.M.J. (author), Ottevanger, Willem (author), Blom, A. (author)A two-dimensional model describing river morphodynamic processes under mixed-size sediment conditions is analysed with respect to its well posedness. Well posedness guarantees the existence of a unique solution continuously depending on the problem data. When a model becomes ill posed, infinitesimal perturbations to a solution grow infinitely...journal article 2019
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Rattanagraikanakorn, B. (author), Schuurman, M.J. (author), Gransden, Derek (author), Happee, R. (author), de Wagter, C. (author), Sharpanskykh, Alexei (author), Blom, H.A.P. (author)Recent developments in the concept of UAS operations in urban areas have led to risk concerns of UAS collision with human. To better understand this risk, head and neck injuries due to UAS collisions have been investigated by different research teams using crash dummies. Because of the limitations in biofidelity of a crash dummy, head injury...conference paper 2019
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Meysman, F.J.R. (author), Cornelissen, Rob (author), Trashin, Stanislav (author), Bonné, Robin (author), van der Veen, J.R. (author), Blom, C.J. (author), Beaumont, H.J.E. (author), van der Zant, H.S.J. (author), Boschker, H.T.S. (author)Biological electron transport is classically thought to occur over nanometre distances, yet recent studies suggest that electrical currents can run along centimetre-long cable bacteria. The phenomenon remains elusive, however, as currents have not been directly measured, nor have the conductive structures been identified. Here we demonstrate...journal article 2019