Topology optimization of differentiable microstructures

Recent years have seen a growing interest in topology optimization of functionally graded microstructures, characterized by an array of microstructures with varying volume fractions. However, microstructures optimized at slightly different volume fractions do not necessarily connect well when placed adjacently. Furthermore, optimization is...

Dynamics of a Tidal Current System in a Marginal Sea: A Case Study of the Yellow Sea, China

Tidal currents belong to the main driving forces shaping the bathymetry of marginal seas. A globally unique radial sand ridge field exists in the South Yellow Sea off the central Jiangsu coast, China. Its formation is related to the distinctive “radial tidal current” pattern at that location. A generally accepted hypothesis is that the ...

Germanene on single-layer ZnSe substrate: Novel electronic and optical properties

In this work, the structural, electronic and optical properties of germanene and ZnSe substrate nanocomposites have been investigated using first-principles calculations. We found that the large direct-gap ZnSe semiconductors and zero-gap germanene form a typical orbital hybridization heterostructure with a strong binding energy, which shows...

The Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor Cells

Purpose: Variations in the radiosensitivity of tumor cells within and between tumors impact tumor response to radiation, including the dose required to achieve permanent local tumor control. The increased expression of DNA-PKcs, a key component of a major DNA damage repair pathway in tumors treated by radiation, suggests that DNA-PKcs– dependent...