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Korounis, D. (author), Durlofsky, L.J. (author), Jansen, J.D. (author), Aziz, K. (author)An adjoint formulation for the gradient-based optimization of oil-gas compositional reservoir simulation problems is presented. The method is implemented within an automatic differentiation-based compositional flow simulator (Stanford's AD-GPRS). The development of adjoint procedures for general compositional problems is much more challenging...journal article 2014