Real-time oncological guidance using diffuse reflectance spectroscopy in electrosurgery: The effect of coagulation on tissue discrimination

In breast surgery, a lack of knowledge about what is below the tissue surface may lead to positive tumor margins and iatrogenic damage. Diffuse reflectance spectroscopy (DRS) is a spectroscopic technique that can distinguish between healthy and tumor tissue making it a suitable technology for intraoperative guidance. However, because tumor...