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Mulla, Yuval (author), Avellaneda, Mario J. (author), Roland, A.P.J. (author), Baldauf, L. (author), Jung, Wonyeong (author), Kim, Taeyoon (author), Tans, S.J. (author), Koenderink, G.H. (author)
Molecular catch bonds are ubiquitous in biology and essential for processes like leucocyte extravasion<sup>1</sup> and cellular mechanosensing<sup>2</sup>. Unlike normal (slip) bonds, catch bonds strengthen under tension. The current paradigm is that this feature provides ‘strength on demand<sup>3</sup>’, thus enabling cells to increase...
journal article 2022
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Perrier, D.L. (author), Vahid Belarghou, A. (author), Kathavi, Vaishnavi (author), Stam, Lotte (author), Rems, L. (author), Mulla, Yuval (author), Muralidharan, A. (author), Koenderink, Gijsje H. (author), Kreutzer, M.T. (author), Boukany, P. (author)
We study the role of a biomimetic actin network during the application of electric pulses that induce electroporation or electropermeabilization, using giant unilamellar vesicles (GUVs) as a model system. The actin cortex, a subjacently attached interconnected network of actin filaments, regulates the shape and mechanical properties of the...
journal article 2019