Pullout Capacity of Single and Biwing Anchors in a Soft Clay Deposit: Model Investigation in a Centrifuge and FEM Predictions

One of the ways to install plate anchors in deep seabed is to drop the anchor system from the sea level and allow it to initially embed in the seabed under its own weight. Further dragging would cause the anchor to rotate and embed further into the seabed. There could be difficulties of getting the anchor plate horizontal or mooring line to...

An anchoring system for supporting platforms for wind energy devices

This paper presents data from an initial development stage of an 'umbrella anchor' concept. The anchor can be pushed into sand deposit in a folded arrangement to reduce installation loads. When a pull-out load is applied to the mooring line, the anchor deploys to create a large embedded plate anchor. Physical modelling was carried out in...

Directed evolution of phosphite dehydrogenase to cycle noncanonical redox cofactors via universal growth selection platform

Noncanonical redox cofactors are attractive low-cost alternatives to nicotinamide adenine dinucleotide (phosphate) (NAD(P)⁺) in biotransformation. However, engineering enzymes to utilize them is challenging. Here, we present a high-throughput directed evolution platform which couples cell growth to the in vivo cycling of a...

Lessons for Remote Post-earthquake Reconnaissance from the 14 August 2021 Haiti Earthquake

On 14th August 2021, a magnitude 7.2 earthquake struck the Tiburon Peninsula in the Caribbean nation of Haiti, approximately 150 km west of the capital Port-au-Prince. Aftershocks up to moment magnitude 5.7 followed and over 1,000 landslides were triggered. These events led to over 2,000 fatalities, 15,000 injuries and more than 137,000...

Tracking fluorescent and ferrimagnetic sediment tracers on an energetic ebb-tidal delta to monitor grain size-selective dispersal

Sediment tracer studies use uniquely identifiable particles to track the pathways and fate of individual sand or silt grains in marine environments. These techniques are best applied to assess connectivity between potential sediment sources and sinks, such as between a sand nourishment and an ecologically sensitive area. Significant challenges...

Centrifuge benchmark testing of laterally loaded monopiles in sand

The large diameter monopile is a commonly used foundation concept for offshore wind turbines. The advantages of geometrical simplicity and reliable performance make it often the most attractive solution. Despite the concept’s high popularity, optimisation of the current design models can still be made. To address fundamental understanding of...

Speech technology for unwritten languages

Speech technology plays an important role in our everyday life. Among others, speech is used for human-computer interaction, for instance for information retrieval and on-line shopping. In the case of an unwritten language, however, speech technology is unfortunately difficult to create, because it cannot be created by the standard...

Monitoring sediment transport patterns on an energetic ebb-tidal delta using dual-signature tracers

Human centromeric CENP-A chromatin is a homotypic, octameric nucleosome at all cell cycle points

Chromatin assembled with centromere protein A (CENP-A) is the epigenetic mark of centromere identity. Using new reference models, we now identify sites of CENP-A and histone H3.1 binding within the megabase, α-satellite repeat-containing centromeres of 23 human chromosomes. The overwhelming majority (97%) of α-satellite DNA is found to be...

Best Practice Guidelines on Surgical Response in Disasters and Humanitarian Emergencies: Report of the 2011 Humanitarian Action Summit Working Group on Surgical Issues within the Humanitarian Space

The provision of surgery within humanitarian crises is complex, requiring coordination and cooperation among all stakeholders. During the 2011 Humanitarian Action Summit best practice guidelines were proposed to provide greater accountability and standardization in surgical humanitarian relief efforts. Surgical humanitarian relief planning...

ICT Innovation and sustainability of the transport sector