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Dubost, Florian (author), Yilmaz, Pinar (author), Adams, Hieab (author), Bortsova, Gerda (author), Ikram, M. Arfan (author), Niessen, W.J. (author), Vernooij, Meike (author), de Bruijne, Marleen (author)
Enlarged perivascular spaces (PVS) are structural brain changes visible in MRI, are common in aging, and are considered a reflection of cerebral small vessel disease. As such, assessing the burden of PVS has promise as a brain imaging marker. Visual and manual scoring of PVS is a tedious and observer-dependent task. Automated methods would...
journal article 2019
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Achterberg, Hakim C. (author), Sørensen, Lauge (author), Wolters, Frank J. (author), Niessen, W.J. (author), Vernooij, Meike W. (author), Ikram, M. Arfan (author), Nielsen, Mads (author), de Bruijne, Marleen (author)
Hippocampal volume and shape are known magnetic resonance imaging biomarkers of neurodegeneration. Recently, hippocampal texture has been shown to improve prediction of dementia in patients with mild cognitive impairment, but it is unknown whether texture adds prognostic information beyond volume and shape and whether the predictive value...
journal article 2019