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van Arendonk, Joyce (author), Yilmaz, Pinar (author), Steketee, Rebecca (author), Zijlmans, Jendé L. (author), Lamballais, Sander (author), Niessen, W.J. (author), Neitzel, Julia (author), Ikram, M. Arfan (author), Vernooij, Meike W. (author)
Brain pathology develops at different rates between individuals with similar burden of risk factors, possibly explained by brain resistance. We examined if education contributes to brain resistance by studying its influence on the association between vascular risk factors and brain pathology. In 4111 stroke-free and dementia-free community...
journal article 2021
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Li, Bo (author), de Groot, Marius (author), Steketee, Rebecca M.E. (author), Meijboom, Rozanna (author), Smits, Marion (author), Vernooij, Meike W. (author), Ikram, M. Arfan (author), Liu, Jiren (author), Niessen, W.J. (author)
Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly characterized from brain diffusion MRI. In addition, to enable analysis of WM tracts in large datasets and in...
journal article 2020
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Vernooij, Meike W. (author), Jasperse, Bas (author), Steketee, Rebecca (author), Koek, M. (author), Vrooman, Henri (author), Ikram, M. Arfan (author), Papma, Janne (author), van der Lugt, Aad (author), Smits, Marion (author), Niessen, W.J. (author)
Objectives: To assesses whether automated brain image analysis with quantification of structural brain changes improves diagnostic accuracy in a memory clinic setting. Methods: In 42 memory clinic patients, we evaluated whether automated quantification of brain tissue volumes, hippocampal volume and white matter lesion volume improves...
journal article 2018