- document
-
Hu, Chunyi (author), Almendros Romero, C. (author), Nam, Ki Hyun (author), Sousa Pires da Costa Basto, R.M. (author), Vink, J.N.A. (author), van Eijkeren-Haagsma, A.C. (author), Bagde, Saket R. (author), Brouns, S.J.J. (author), Ke, Ailong (author)Prokaryotes adapt to challenges from mobile genetic elements by integrating spacers derived from foreign DNA in the CRISPR array<sup>1</sup>. Spacer insertion is carried out by the Cas1–Cas2 integrase complex<sup>2–4</sup>. A substantial fraction of CRISPR–Cas systems use a Fe–S cluster containing Cas4 nuclease to ensure that spacers are...journal article 2021
- document
-
Roelofsen, C.P.G. (author), Jansen, K.M.B. (author), Vink, P. (author)For sedentary activities, the PMV equation, derived by Fanger, is mainly based on the research of Nevins et al. (720 test subjects). Nevins' experiments were later on repeated by Fanger, but with 128 college-age Danish subjects and 128 elderly Danish subjects, instead of American subjects. Rohles did the research from Nevins et al. again, but...journal article 2021
- document
-
Roelofsen, C.P.G. (author), Jansen, K.M.B. (author), Vink, P. (author)There are different thermal perception models linked to a mathematical thermophysiological human model, with which the thermal sensation under stationary and/or dynamic conditions can be evaluated. Each of these perception and thermophysiological models have their own field of application. Stolwijk developed a thermophysiological human model...journal article 2021
- document
-
van Beljouw, S.P.B. (author), van Eijkeren-Haagsma, A.C. (author), Rodriguez Molina, A. (author), van den Berg, D.F. (author), Vink, J.N.A. (author), Brouns, S.J.J. (author)Type III CRISPR-Cas immunity is widespread in prokaryotes and is generally mediated by multisubunit effector complexes. These complexes recognize complementary viral transcripts and can activate ancillary immune proteins. Here, we describe a type III-E effector from Candidatus “Scalindua brodae” (Sb-gRAMP), which is natively encoded by a...journal article 2021
- document
-
Fiorillo, Iolanda (author), Song, Y. (author), Vink, P. (author), Naddeo, Alessandro (author)Remaining seated for extended periods increases the risk health issues and discomfort perception. Consequently, the seat-pan design is crucial and could be mainly influenced by two factors: pressure distribution and seat contour. For seat pan discomfort, the lower average pressure is accompanied by less discomfort. Moreover, a seat contour...journal article 2021
- document
-
van Dorst, M.J. (author), Vink, J.A. (author), van der Wal, I.A. (author), Darras, H. (author), Lopez, H. (author), Ringel, R. (author)De visie gemeenschappelijke voorzieningen is tussen oktober 2020 en maart 2021 ontwikkeld in opdracht van de stuurgroep Gemeenschappelijke Voorzieningen van de TU Delft. De opdracht was de volgende: ‘het ontwikkelen van een langetermijnvisie waarmee beslissingen over de gemeenschappelijke voorzieningen genomen kunnen worden’. Deze publicatie...report 2021
- document
-
Dekker, M.C. (author), van Egmond, R. (author), Molenbroek, J.F.M. (author), Vink, P. (author)BACKGROUND: Former studies on work-related upper limb disorders (WRULD) within university education report substantial prevalence rates. In this study, developments in WRULD amongst students in the period 2004-2014 were investigated. Our findings can be a benchmark for future studies, in particular when there are major societal changes as in...journal article 2021
- document
-
Di Brigida, Liliana (author), Fiorillo, Iolanda (author), Naddeo, Alessandro (author), Vink, P. (author)This study aimed to analyse the discomfort threshold (that could be linked to sensitivity or sensation) of different regions in hand and elbow to support hand-held devices' design. Indeed, there are no studies regarding the hand and elbow discomfort threshold or sensitivity. To overcome these literature gaps, the discomfort threshold of hand...conference paper 2021
- document
-
Han, L. (author), Zhang, Hechen (author), Xiang, Zhongxia (author), Shang, J. (author), Anjani, S. (author), Song, Y. (author), Vink, P. (author)BACKGROUND: The contrast between a bright computer screen and a dark ambient environment may influence comfort of the users, especially on their eyes. OBJECTIVE: The objective of this research is to identify the optimal desktop lighting for the comfortable use of the computer screen in a dark environment. METHODS: An experiment was designed...journal article 2021
- document
-
Anjani, S. (author), Kühne, Manon (author), Naddeo, Alessandro (author), Frohriep, Susanne (author), Mansfield, Neil (author), Song, Y. (author), Vink, P. (author)BACKGROUND: Selecting the most suitable questionnaire(s) in comfort research for product design is always a challenge, even for experienced researchers. OBJECTIVE: The objective of this research is to create a list of Preferred Comfort Questionnaires (PCQ) for product design to help researchers in the selection of questionnaires for comfort...journal article 2021
- document
-
Anjani, S. (author), Song, Y. (author), Hou, T. (author), Ruiter, I.A. (author), Vink, P. (author)The pitch and width of airline seats are crucial factors on the comfort of passengers. The aim of this study is to measure the comfort feeling of passengers regarding different widths and together with data from a previous study, to offer suggestions on the aircraft interior design. 311 participants were recruited and were asked to sit in 17...journal article 2021
- document
-
Vink, P. (author), Anjani, S. (author), Netten, M.P. (author), de Ree, H. (author), de Haan, A (author), Song, Y. (author)Discomfort was recorded by 26 airline pilots during flight. Thirteen reported their discomfort during a long haul flight and 13 completed the questionnaires during short haul flights. Discomfort values increased with time to high values, but with a modest decrease towards the end of the flight. Most discomfort was reported in the low back area....conference paper 2021
- document
-
Anjani, S. (author), Song, Y. (author), Vink, P. (author)BACKGROUND: Recent research indicated that an 18′′ ×30′′ aircraft seat resulted in nearly the same level of comfort as a 17′′ ×34′′ seat. However, it took less space in the floor plan. OBJECTIVES: This study explores seat layouts preferred by experts regarding different criteria. Those results of the experts are later compared to layouts...journal article 2021
- document
-
Vink, P. (author), Anjani, S. (author), Percuoco, C. (author), Vos, Roelof (author), Vanacore, Amalia (author)Staggered seats might be a solution for a V-shaped aircraft (the Flying V). The cabin longitudinal axis of this airplane has a 26° angle with respect to the direction of flight. When seats are positioned in the direction of flight, they consequently have an angle to the cabin and become staggered. It is unknown whether the comfort of this...conference paper 2021
- document
-
Liu, Z. (author), Rotte, T.A. (author), Anjani, S. (author), Vink, P. (author)BACKGROUND: Staggered seats are a solution for the Flying-V aircraft, where the cabin's longitudinal axis has a 26 degrees angle with respect to the direction of flight, to compensate for an otherwise oblique sitting position. However, little is known on acceptable pitches in this staggered configuration. OBJECTIVE: The goal of this research...journal article 2021
- document
-
Vink, M.G. (author), Koorstra, P.A. (author)Een serie kleine abstracte vormen staat op een werktafel in het midden van de studio. Een groep studenten staat om de tafel en één voor één plaatsen zij hun werk in een grote maquette waar een stuk stad in te herkennen is. Er wordt aandachtig gekeken terwijl er steeds een nieuwe vorm onderdeel van dat stuk stad wordt. Ieder volume wordt...book chapter 2020
- document
-
He, Z. (author), Vink, P. (author)Sleeping in long haul flights is difficult. There is noise, an upright sitting position and neighbors and crew disturb the sleep. However, there is not much information available for designers on the most important factors next to the seat that could improve the sleep quality. In this paper a co-creation session and a survey among 109...journal article 2020
- document
-
Vink, J. (author), Santos, Bruno F. (author), Verhagen, W.J.C. (author), Medeiros, I. (author), Filho, R. (author)This paper presents a new approach for solving the recovery of the airline schedule when disruptions have occurred. The goal is to develop an operational tool that provides the airline with a solution in less than one minute. The proposed recovery model uses a heuristic that iteratively solves selections of the airline's fleet in order to...journal article 2020
- document
-
Anjani, S. (author), Li, W. (author), Ruiter, I.A. (author), Vink, P. (author)This study explores the relationship between seat pitch and comfort, and the influencing factors, like space experience and anthropometric measurements. Two hundred ninety-four participants experienced economy class seats in a Boeing 737 with 28-inch, 30-inch, 32-inch and 34-inch seat pitches. Anthropometric measurements of the participants...journal article 2020
- document
-
Vink, P. (author), Anjani, S. (author), Udomboonyanupap, S. (author), Torkashvand, Golnoosh (author), Albin, T.J. (author), Miguez, Symone (author), Li, Wenhua (author), Reuter, Christian (author), Vanacore, Amalia (author)In order to investigate differences in comfort and discomfort experiences amongst different regions of the world (America, Asia and Europe), a cross cultural study was performed. A questionnaire was sent to participants out in nine countries (Brazil, Canada, the USA, China, Indonesia, Thailand, Germany, Italy and the Netherlands). In total...journal article 2020