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Brown, Michael D. (author), Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), Koekkoek, Sebastiaan K.E. (author), Strydis, C. (author), Bosch, Johannes G. (author), Arvanitis, Petros (author), Springeling, Geert (author), Leus, G.J.T. (author), De Zeeuw, Chris I. (author), Kruizinga, P. (author)Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), an imaging method that uses complex ultrasound fields that can be generated with simple hardware and a physical wave prediction...journal article 2024
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Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), Bosman, Laurens W.J. (author), De Zeeuw, Chris I. (author), Koekkoek, Sebastiaan K.E. (author), Kruizinga, P. (author)Functional ultrasound (fUS) using a 1-D-array transducer normally is insufficient to capture volumetric functional activity due to being restricted to imaging a single brain slice at a time. Typically, for volumetric fUS, functional recordings are repeated many times as the transducer is moved to a new location after each recording, resulting...journal article 2023
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Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), De Zeeuw, Chris I. (author), Koekkoek, Sebastiaan K.E. (author), Kruizinga, P. (author)Volumetric 3-D Doppler ultrasound imaging can be used to investigate large scale blood dynamics outside of the limited view that conventional 2-D power Doppler images (PDIs) provide. To create 3-D PDIs, 2-D-matrix array transducers can be used to insonify a large volume for every transmission; however, these matrices suffer from low...journal article 2023
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van der Meulen, P.Q. (author), Coutino, Mario (author), Bosch, Johannes G. (author), Kruizinga, P. (author), Leus, G.J.T. (author)We consider the scenario of finding the transfer function of an aberrating layer in front of a receiving ultrasound (US) array, assuming a separate non-aberrated transmit source. We propose a method for blindly estimating this transfer function without exact knowledge of the ultrasound sources or acoustic contrast image, and without directly...journal article 2023
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Erol, A. (author), Generowicz, Bastian (author), Kruizinga, P. (author), Hunyadi, Borbala (author)Functional ultrasound (fUS) is an emerging neuroimaging modality that indirectly measures neural activity by detecting fluctuations in local blood dynamics. fUS acquisitions typically rely on the use of a 1D array transducer, which records hemodynamic activity in a single plane. A new technique named swept-3D fUS imaging obtains a full 3D...conference paper 2023
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Wijnands, R. (author), Dauwels, J.H.G. (author), Serra, Ines (author), Kruizinga, P. (author), Badura, Aleksandra (author), Hunyadi, Borbala (author)Functional ultrasound (fUS) is a novel neuroimaging technique that measures brain hemodynamics through a time series of Doppler images. The measured spatiotemporal hemodynamic changes reflect changes in neural activity through the neurovascular coupling (NVC). Often, such image time series is used to analyze dynamic functional connectivity ...conference paper 2023
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Lehmann, Isabell (author), Adali, Tulay (author), Kruizinga, P. (author), Hunyadi, Borbala (author)Functional Ultrasound (fUS) is a relatively new modality to measure brain activity with a high spatio-temporal resolution. In order to collect full-brain information with this 2D imaging technique, fUS data is typically collected for a fixed position of the ultrasound probe for the duration of the experiment, before the probe is moved to the...conference paper 2023
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Hu, Yuyang (author), Doğan, D. (author), Brown, Michael (author), Bulot, Mahé (author), Ferin, Guillaume (author), Leus, G.J.T. (author), Kruizinga, P. (author), Steen, Antonius F.W. (author), Bosch, Johannes G. (author)It has been previously demonstrated that applying an aberrating mask for 2D compressive imaging using a low number of sensors (elements) can significantly improve image resolution, as evaluated via the point spread function. Here we investigate the potential to apply a similar approach for 3D flow monitoring. We conducted a 3D k-Wave simulation...conference paper 2023
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Hu, Yuyang (author), Brown, Michael (author), Doğan, D. (author), Leus, G.J.T. (author), Kruizinga, P. (author), Van Der Steen, Antonius F.W. (author), Bosch, Johannes G. (author)We intend to develop an ultrasound compressive imaging device to perform carotid artery (CA) function and flow monitoring/imaging by using just a few single element transducers equipped with spatial coding masks. The spatially unique impulse responses can be exploited in compressive reconstructions. To explore the potential of different...conference paper 2022
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Erol, A. (author), Soloukey, Chagajeg (author), Generowicz, Bastian (author), van Dorp, Nikki (author), Koekkoek, Sebastiaan (author), Kruizinga, P. (author), Hunyadi, Borbala (author)The original version of this article was revised to update the Figure 8 (panel B) image. The correct image should have a yellow shape as presented below. (Figure presented.). The original article has been corrected.journal article 2022
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Erol, A. (author), Soloukey, Chagajeg (author), Generowicz, Bastian (author), van Dorp, Nikki (author), Koekkoek, Sebastiaan (author), Kruizinga, P. (author), Hunyadi, Borbala (author)Functional ultrasound (fUS) indirectly measures brain activity by detecting changes in cerebral blood volume following neural activation. Conventional approaches model such functional neuroimaging data as the convolution between an impulse response, known as the hemodynamic response function (HRF), and a binarized representation of the input...journal article 2022
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Siddiqi, M.A. (author), Beurskens, Robert H.S.H. (author), Kruizinga, Pieter (author), De Zeeuw, Chris I. (author), Strydis, C. (author)Modern Implantable Medical Devices (IMDs) are vulnerable to security attacks because of their wireless connectivity to the outside world. One of the main security challenges is establishing trust between the IMD and an external reader/programmer in order to facilitate secure communication. Numerous device-pairing schemes have been proposed to...journal article 2021
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Doğan, D. (author), Kruizinga, P. (author), Bosch, Johannes G. (author), Leus, G.J.T. (author)Ultrasound imaging of the vasculature has major significance for the detection of cardiovascular diseases and cancer. However, limited spatial resolution or long acquisition times of existing techniques limit the visualization of the microvascular structures. Enforcing sparsity in the underlying vasculature as well as exploiting statistical...conference paper 2021
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, Johannes G. (author), Leus, G.J.T. (author)We study the design of a coding mask for pulse-echo ultrasound imaging. We are interested in the scenario of a single receiving transducer with an aberrating layer, or ‘mask,’ in front of the transducer's receive surface, with a separate co-located transmit transducer. The mask encodes spatial measurements into a single output signal, containing...journal article 2020
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Erol, A. (author), Eyndhoven, Simon Van (author), Koekkoek, Sebastiaan (author), Kruizinga, P. (author), Hunyadi, Borbala (author)Functional ultrasound (fUS) is an exciting new neuroimaging technique that is able to record brain activity similar to functional magnetic resonance imaging, yet with higher spatiotemporal resolution and at lower cost. We consider the problem of jointly estimating the underlying neural sources and the hemodynamic response function (HRF) from fUS...conference paper 2020
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van der Meulen, P.Q. (author), Coutino, Mario (author), Kruizinga, P. (author), Bosch, J.G. (author), Leus, G.J.T. (author)We consider the scenario of finding the transfer function of an aberrating layer in front of an ultrasound array. We are interested in blindly estimating this transfer function without prior knowledge of the unknown ultrasound sources or ultrasound contrast image. The algorithm gives an exact solution if the matrix representing the aberration...conference paper 2020
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Iskander-Rizk, Sophinese (author), Kruizinga, P. (author), Beurskens, Robert (author), Springeling, Geert (author), Mastik, Frits (author), de Groot, N.M.S. (author), Knops, Paul (author), van der Steen, A.F.W. (author), van Soest, Gijs (author)In interventional electrophysiology, catheter-based radiofrequency (RF) ablation procedures restore cardiac heart rhythm by interrupting aberrant conduction paths. Real-time feedback on lesion formation and post-treatment lesion assessment could overcome procedural challenges related to ablation of underlying structures and lesion gaps. This...journal article 2019
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, Johannes G. (author), Leus, G.J.T. (author)We consider a model-based ultrasound imaging scenario using a single transducer with a coding mask, and assume that the pulse-echo model is erroneously estimated, resulting in decreased imaging performance. Although the pulse-echo Green's function to each pixel has to be measured to obtain a good model, typically only forward-field...conference paper 2019
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, J.G. (author), Leus, G.J.T. (author)We study the optimal design of an aperture coding mask, and the optimal sensing positions of a single ultrasound sensor with a scanning configuration. In previous works, we have shown that 3D ultrasound imaging is possible using a randomly shaped coding mask with randomly chosen sensing positions. Here we propose an optimization algorithm for...conference paper 2018
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Kang, E. (author), Ding, Q. (author), Shabanimotlagh, M. (author), Kruizinga, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, J.W. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) designed for 3-D ultrasonic imaging of the carotid artery. This application calls for an array of thousands of ultrasonic transducer elements, far exceeding the number of channels of conventional imaging systems. The 3.6 x 6.8 mm² ASIC...journal article 2018
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