Synergistic effects of cerium-containing bioactive glasses and apoptotic extracellular vesicles alleviate bisphosphonate-related osteonecrosis of jaw

Bisphosphonates (BPs) are commonly used to treat skeletal diseases. However, long-term use of BPs can lead to BP-related jaw bone necrosis (BRONJ), particularly in patients undergoing tooth extraction surgery. The treatment of BRONJ remains challenging due to the local inflammatory microenvironment. To address this issue, we developed...

Distinctive sedimentary processes on two contrasting tidal flats of the Yellow River Delta

Coastal tidal flats provide valuable ecosystems, but are highly sensitive to tidal dynamics, sea-level rise, and human activities. Tidal inundation depth and frequency are known to affect tidal flat morphodynamics. However, the causes, processes and extent remain uncertain, particularly given the associated changes in sediment availability. In...

Reclamation of Tidal Flats Within Tidal Basins Alters Centennial Morphodynamic Adaptation to Sea-Level Rise

Reclamation of low-lying tidal flats and floodplains adjacent to present shorelines has been implemented worldwide for both coastal defense and development. While it is technically feasible to monitor the short-term impact of tidal flat embankments, it is challenging to identify long-term and cumulative morphodynamic impact, particularly...

Novel Solid-State Sodium-Ion Battery with Wide Band Gap NaTi₂(PO₄)₃ Nanocrystal Electrolyte

NaTi2(PO4)3 (NTP), a well-known anode material, could be used as a solid wide-band gap electrolyte. Herein, a novel solid-state sodium-ion battery (SSIB) with the thickness of electrolyte up to the millimeter level is proposed. The results of the difference in charge density investigated by the first-principles calculations imply that using...

Identifying how future climate and land use/cover changes impact streamflow in Xinanjiang Basin, East China

Climate and land use/cover changes are the main factors altering hydrological regimes. To understand the impacts of climate and land use/cover changes on streamflow within a specific catchment, it is essential to accurately quantify their changes given many possibilities. We propose an integrated framework to assess how individual and...