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Shang, Y. (author), Nogal Macho, M. (author), Teixeira, Rui (author), Wolfert, A.R.M. (author)The use of sensitivity analysis is essential in model development for the purposes of calibration, verification, factor prioritization, and mechanism reduction. While most contributions to sensitivity methods focus on the average model response, this paper proposes a new sensitivity method focusing on the extreme response and structural limit...journal article 2023
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Klerk, W.J. (author), van Bergeijk, Vera (author), Kanning, W. (author), Wolfert, A.R.M. (author), Kok, M. (author)The condition of flood defence revetments is influenced by many different degradation processes such as animal burrowing, rutting and growth of weeds. Many of these processes are shock-based rather than progressive continuous. As shocks can cause a drop in performance, this means that the condition of a revetment can suddenly decrease,...journal article 2023
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Wolfert, A.R.M. (author)Current systems design and decision management methodologies can be single-sided, ignoring or failing to capture the dynamic interplay between multi-stakeholder preferences (‘what they want’) and system performances (‘what they can’). In addition, these methodologies often contain fundamental modelling errors and do not provide single best-fit...book 2023
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Shang, Y. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Improvement in rail asset safety, comfortability and serviceability is gaining importance. This requires effective service life management by incorporating multi-stakeholder desires in the early design stage. Typical stakeholders are asset owners, train users and maintenance service providers. To allow for this change, the traditional single...conference paper 2023
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van Heukelum, H.J. (author), Steenbrink, A.C. (author), Colomés, Oriol (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Floating wind farms are a promising solution for offshore wind energy production in deep waters. However, the design optimisation process of these farms is difficult due to their complex and multidisciplinary nature. Furthermore, current optimisation methods: 1) ignore and/or provide no insight into the dynamic interplay between the preference...conference paper 2023
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Shang, Y. (author), Nogal Macho, M. (author), Teixeira, Rui (author), Wolfert, A.R.M. (author)Transition zones such as level crossing and bridge approaches are critical links in railway networks due to higher degradation rates and maintenance needs. In this context, parametric optimization has been applied to improve the design in transition zones; however, it requires a more computationally efficient tool to support repetitive...journal article 2023
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Zhilyaev, D. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Within traditional design processes, decisions are often made based on individualistic values and late-stage assessments conducted on a predefined set of design alternatives potentially leading to suboptimal design decisions and conflicts. The issues are further amplified by the growing complexity of construction project management where an...journal article 2022
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Wolfert, A.R.M. (author), van Nederveen, G.A. (author), Binnekamp, R. (author)Building Information Models (BIM) should reflect all aspects and phases of the construction projects life cycle. However, in current contractor practices, a proliferation of different information systems has arisen, each of which in turn illuminates a different information model dimension (nD) for usually only one construction project management...journal article 2022
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Shang, Y. (author), Nogal Macho, M. (author), Wolfert, A.R.M. (author)A co-simulation solution based on direct equilibrium of contact forces is proposed to simulate vehicle-track interaction (VTI) dynamics. It is developed in two platforms, which presents an iterative feedback loop that exchanges contact force files and structure response field in real-time. The load vector acting on the structure is described by...book chapter 2022
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Kammouh, O. (author), Kok, M.W.A. (author), Nogal Macho, M. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Changes in a construction project schedule can impact the project's planned duration, resulting in penalties. A manual trial-and-error probabilistic approach is usually conducted to find an appropriate set of corrective measures to mitigate delays of the overall project. However, this approach does not capture the actual goal-oriented...journal article 2022
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Cecotto, Leonardo (author), van Kessel, Kok (author), Wolfert, Margreet A. (author), Vogely, Charles (author), van der Wal, Bart (author), Weinans, Harrie (author), van Strijp, Jos (author), Amin Yavari, S. (author)Cationic host defense peptides (HDPs) are a promising alternative to antibiotics in the fight against Staphylococcus aureus infections. In this study, we investigated the antibacterial and immunomodulatory properties of three HDPs namely IDR-1018, CATH-2, and LL-37. Although all three HDPs significantly inhibited LPS-induced activation of...journal article 2022
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Kammouh, O. (author), Nogal Macho, M. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Construction project management requires dynamic mitigation control to ensure a project's timely completion. Current mitigation approaches are usually performed by an iterative Monte Carlo (MC) analysis which does not reflect (1) the project manager's goal-oriented behavior, (2) contractual project completion performance schemes, and (3)...journal article 2022
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Shang, Y. (author), Nogal Macho, M. (author), Wang, Haoyu (author), Wolfert, A.R.M. (author)Performance evaluation and maintenance planning are gaining importance with ageing rail infrastructure and increasing demand on track safety and continuous availability. The discrete/point railway assets (e.g. bridges, level crossings) together with extended track sections constitute the main railway network infrastructure. The former has...journal article 2021
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Klerk, W.J. (author), Kanning, W. (author), Kok, M. (author), Wolfert, A.R.M. (author)Climate change and deterioration require a continuous effort to reinforce flood defences and meet reliability requirements. To efficiently upgrade flood defence systems, insight in costs and benefits of measures at a system level is required throughout the process of planning and design. Due to the size of flood defence systems the number of...journal article 2021
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Kammouh, O. (author), Nogal Macho, M. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Probabilistic Monte Carlo simulations are often used to determine a project's completion time given a required probability level. During project execution, schedule changes negatively affect the probability of meeting the project's completion time. A manual trial and error approach is then conducted to find a set of mitigation measures to...journal article 2021
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Klerk, W.J. (author), Kanning, W. (author), Kok, M. (author), Bronsveld, J. (author), Wolfert, A.R.M. (author)Prioritisation of flood defence maintenance is typically based on visual inspection. However, literature shows that the Probability of Detection (PoD) of visual inspection can vary significantly. Here we investigate the PoD for visual inspections of flood defence structures, the consistency of damage classification, and the influence of...journal article 2021
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Kammouh, O. (author), Nogal Macho, M. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)The wellbeing of modern societies is dependent upon the functioning of their infrastructure networks. This paper introduces the 3C concept, an integrative multi-system and multi-stakeholder optimization approach for managing infrastructure interventions (e.g., maintenance, renovation, etc.). The proposed approach takes advantage of the...journal article 2021
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Wijs, R. J.A. (author), Nane, G.F. (author), Leontaris, G. (author), Van Manen, T. R.W. (author), Wolfert, A.R.M. (author)Utility operators must rely on predictive analyses regarding the availability of their subsurface assets, which highly depend on damage by increasing amounts of excavation work. However, straightforward use of standard statistical techniques, such as logistic regression or Bayesian logistic regression, does not allow for accurate predictions...journal article 2020
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Kammouh, O. (author), Nogal Macho, M. (author), Cimellaro, Gian Paolo (author), Wolfert, A.R.M. (author)The capacity of a community to react to and resist during an emergency situation is highly related to the proper functioning of its infrastructure systems. Improving the infrastructure response and recovery capacity through management and adaptation strategies can help increase community resilience. Infrastructural assets are considered outdated...conference paper 2020
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Kammouh, O. (author), Nogal Macho, M. (author), de Bruijne, M.L.C. (author), Binnekamp, R. (author), Wolfert, A.R.M. (author)Despite widespread attention for the governance of infrastructures and improvements of the way infrastructure assets are maintained, the interdependency of infrastructures is not often considered from a systemic maintenance and renovation perspective. In this context, the issue of unforeseen intervention delays is of particular relevance because...conference paper 2020
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