Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Metabolomics examines the small molecules involved in cellular metabolism. Approximately 50% of total phenotypic differences in metabolite levels is due to genetic variance, but heritability estimates differ across metabolite classes. We perform a review of all genome-wide association and (exome-) sequencing studies published between November...

On Untethered, Dual Magneto- and Photoresponsive Liquid Crystal Bilayer Actuators Showing Bending and Rotating Motion

The integration of untethered, multi-stimuli responsive actuation into soft microrobotic devices is a goal in the development of “smart” materials. This manuscript reports on a dual-stimuli responsive bilayer actuator consisting of a light responsive liquid crystal network (LCN) and a magnetic responsive polydimethylsiloxane (PDMS) composite....

Effect of thermal cycling heated Fibre Metal Laminates under static load

Heated GLARE, a Fibre Metal Laminate with an integrated heater element, has been developed for de- or anti-icing systems in aircraft structures. Besides cyclic thermal loading these structures are also subjected to mechanical loading. To investigate the effect of static loading in addition to thermal cycling a series of tests have been performed...

Effect of long-term thermal cycling and moisture on heated Fibre Metal Laminates and glass-fibre epoxy composites

Heated GLARE, a Fibre Metal Laminate with an integrated heater element, has a promising potential as de- or anti-icing system in aircraft structures. To investigate the long-term durability of heated GLARE previously reported thermal cycling tests up to 12,000 cycles are extended up to 144,000 cycles and moisture conditioning is included....

Controlling the edge effect using a bypass conductor for induction welding of carbon fibre thermoplastic composites

Carbon fibre thermoplastic composites can be induction welded thanks to the electrical conductive nature of carbon fibre. Due to a locally contrained current flow more heat is generated at the edges of the composites. To counteract this so called edge effect a highly conductive material is attached to the edge to create an electrical bypass. The...

Effect of Thermal Cycling and Aging on Heated Fiber Metal Laminates and Glass-Fiber Epoxy Composites

By integrating heater elements in Fiber Metal Laminates, such as GLARE, the material has a promising potential as de- or anti-icing system in aircraft structures. Application of this so called "heated GLARE" material will however result in increase and (up to ten fold) more frequent temperature loading compares to the regular flight...

Thermal cycling of (heated) fibre metal laminates

Fibre metal laminates with integrated heater elements have a promising potential as de- or anti-icing systems in aircraft structures. The alternating metal and composite lay-up in fibre metal laminates seems ideal for the development of a multifunctional skin with embedded heater elements. However, the long term durability needs to be carefully...

Monitoring chemical degradation of thermally cycled glass-fibre composites using hyperspectral imaging

Nowadays, the application of glass-fibre composites in light-weight structures is growing. Although mechanical characterizations of those structures are commonly performed in testing, chemical changes of materials under stresses have not yet been well documented. In the present work coupon tests and Hyperspectral Imaging (HSI) have been used to...

Characterisation of fibre metal laminates under thermomechanical loadings

Fibre metal laminates, such as Arall or Glare, can offer improved properties compared to monolithic materials. Glare for example shows improved fatigue, residual strength, burn-through, impact and corrosion properties with respect to aluminium 2024, together with a considerable weight reduction and competitive costs. A large research program has...