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Ganjian, M. (author), Angeloni, L. (author), Mirzaali, Mohammad J. (author), Modaresifar, K. (author), Hagen, C.W. (author), Ghatkesar, M.K. (author), Hagedoorn, P.L. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)One of the methods to create sub-10 nm resolution metal-composed 3D nanopillars is electron beam-induced deposition (EBID). Surface nanotopographies (e.g., nanopillars) could play an important role in the design and fabrication of implantable medical devices by preventing the infections that are caused by the bacterial colonization of the...journal article 2020
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Hagen, Jenny Sjåstad (author), Cutler, Andrew (author), Trambauer, Patricia (author), Weerts, Albrecht (author), Suarez, Pablo (author), Solomatine, D.P. (author)Forecast-based financing is a financial mechanism that facilitates humanitarian actions prior to anticipated floods by triggering release of pre-allocated funds based on exceedance of flood forecast thresholds. This paper presents a novel model suitability matrix that embeds application-specific needs and contingencies at local level on a...journal article 2020
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Hagen, N. (author)A belt conveyor system is a commonly used mean of transportation for dry bulk material. The system components are subjected to wear because of the multiple rotating components. This will result in component failures on the long run. Maintenance or replacement actions are required for these components in order to prevent these system failures. In...report 2019
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Arat, K.T. (author), Klimpel, Thomas (author), Zonnevylle, A.C. (author), Ketelaars, Wilhelmus S.M.M. (author), Heerkens, C.T.H. (author), Hagen, C.W. (author)Electron beam lithography (EBL) requires conducting substrates to ensure pattern fidelity. However, there is an increasing interest in performing EBL on less well-conducting surfaces or even insulators, usually resulting in seriously distorted pattern formation. To understand the underlying charging phenomena, the authors use Monte Carlo...journal article 2019
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Hagen, W.R. (author)Over half a century ago the hypothesis was put forth that redox-active metal ions and multidentate protein ligands may combine to form a local state of entasis: an irregular symmetry intermediate between those dictated by coordination chemistry for the two redox states involved. Such an energetically poised domain would be at the basis of high...review 2019
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Arat, K.T. (author), Klimpel, Thomas (author), Hagen, C.W. (author)Background: Charging of insulators is a complex phenomenon to simulate since the accuracy of the simulations is very sensitive to the interaction of electrons with matter and electric fields. Aim: In this study, we report model improvements for a previously developed Monte-Carlo simulator to more accurately simulate samples that charge....journal article 2019
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Hagen, W.R. (author)Analysis of the electron paramagnetic resonance (EPR) of transition ion complexes requires data taken at different microwave frequencies because the spin Hamiltonian contains operators linear in the frequency as well as operators independent of the frequency. In practice, data collection is hampered by the fact that conventional EPR...journal article 2019
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van Kessel, L.C.P.M. (author), Hagen, C.W. (author), Kruit, P. (author)Background: Monte Carlo simulations of scanning electron microscopy (SEM) images ignore most surface effects, such as surface plasmons. Previous experiments have shown that surface plasmons play an important role in the emission of secondary electrons (SEs).Aim: We investigate the influence of incorporating surface plasmons into simulations...journal article 2019
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Hesam Mahmoudi Nezhad, N. (author), Ghaffarian Niasar, M. (author), Mohammadi Gheidari, A. (author), Hagen, C.W. (author), Kruit, P. (author)In electrostatic charged particle lens design, optimization of a multi-electrode lens with many free optimization parameters is still quite a challenge. A fully automated optimization routine is not yet available, mainly because the lens potential calculations are often done with very time-consuming methods that require meshing of the lens...journal article 2019
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Dimitrijević, Milena S. (author), Bogdanović Pristov, Jelena (author), Žižić, Milan (author), Stanković, Dalibor M. (author), Bajuk-Bogdanović, Danica (author), Stanić, Marina (author), Spasić, Snežana (author), Hagen, W.R. (author), Spasojević, Ivan (author)Biliverdin (BV), a product of heme catabolism, is known to interact with transition metals, but the details of such interactions under physiological conditions are scarce. Herein, we examined coordinate/redox interactions of BV with Cu <sup>2+</sup> in phosphate buffer at pH 7.4, using spectrophotometry, HESI-MS, Raman spectroscopy, <sup>1<...journal article 2019
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Widyaratih, Dwisetya S. (author), Hagedoorn, P.L. (author), Otten, L.G. (author), Ganjian, M. (author), Tümer, N. (author), Apachitei, I. (author), Hagen, C.W. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)Recent discoveries have shown that nanopatterns with feature sizes ≤100 nm could direct stem cell fate or kill bacteria. These effects could be used to develop orthopedic implants with improved osseointegration and decreased chance of implant-associated infections. The quest for osteogenic and bactericidal nanopatterns is ongoing but no...journal article 2019
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Ganjian, M. (author), Modaresifar, K. (author), Ligeon, Manon R.O. (author), Kunkels, Lorenzo B. (author), Tümer, N. (author), Angeloni, L. (author), Hagen, C.W. (author), Otten, L.G. (author), Hagedoorn, P.L. (author), Apachitei, I. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)Development of synthetic bactericidal surfaces is a drug-free route to the prevention of implant-associated infections. Surface nanotopographies with specific dimensions have been shown to kill various types of bacterial strains through a mechanical mechanism, while regulating stem cell differentiation and tissue regeneration. The effective...journal article 2019
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Arat, K.T. (author), Bolten, Jens (author), Zonnevylle, A.C. (author), Kruit, P. (author), Hagen, C.W. (author)Scanning electron microscopy (SEM) is one of the most common inspection methods in the semiconductor industry and in research labs. To extract the height of structures using SEM images, various techniques have been used, such as tilting a sample, or modifying the SEM tool with extra sources and/or detectors. However, none of these techniques...journal article 2019
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Subramanian, Kalyanasundaram (author), Mitusińska, Karolina (author), Raedts, John (author), Almourfi, Feras (author), Joosten, Henk Jan (author), Hendriks, Sjon (author), Sedelnikova, Svetlana E. (author), Kengen, Servé W.M. (author), Hagen, W.R. (author)The cupin-type phosphoglucose isomerase (PfPGI) from the hyperthermophilic archaeon Pyrococcus furiosus catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate. We investigated PfPGI using protein-engineering bioinformatics tools to select functionally-important residues based on correlated mutation analyses. A...journal article 2019
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van Kessel, L.C.P.M. (author), Hagen, C.W. (author), Kruit, P. (author)We have investigated the contributions of surface effects to Monte Carlo simulations of top-down scanning electron microscopy (SEM) images. The elastic and inelastic scattering mechanisms in typical simulations assume that the electron is deep in the bulk of the material. In this work, we correct the inelastic model for surface effects. We...conference paper 2019
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Hari, S. (author), Verduin, T. (author), Kruit, P. (author), Hagen, C.W. (author)The potential of Electron Beam Induced Deposition (EBID) to become a reliable and reproducible direct-write nanopatterning technique has been investigated. A key requirement is that patterns of sub-20 nm dimension can be reproducibly fabricated and measured. EBID was used for the controlled fabrication of sub-20 nm dense lines on bulk silicon...journal article 2019
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Arat, K.T. (author), Zonnevylle, A.C. (author), Ketelaars, Wilhelmus S.M.M. (author), Belic, Nikola (author), Hofmann, Ulrich (author), Hagen, C.W. (author)There is a growing interest for patterning on curved or tilted surfaces using electron beam lithography. Computational proximity correction techniques are well established for flat surfaces and perpendicular exposure, but for curved and tilted surfaces adjustments are needed as the dose distribution is no longer cylindrically symmetric with...journal article 2019
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Hagen, W.R. (author)From the very first discovery of biological iron–sulfur clusters with EPR, the spectroscopy has been used to study not only purified proteins but also complex systems such as respiratory complexes, membrane particles and, later, whole cells. In recent times, the emphasis of iron–sulfur biochemistry has moved from characterization of...journal article 2018
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Arat, K.T. (author), Klimpel, T. (author), Hagen, C.W. (author)Charging of insulators is a complex phenomenon to simulate since the accuracy of the simulations is very sensitive to the interaction of electrons with matter and electric fields. In this study, we report model improvements for a previously developed Monte-Carlo simulator to more accurately simulate samples that charge. The improvements...conference paper 2018
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- Swiderek, Petra (author), Marbach, Hubertus (author), Hagen, C.W. (author) contribution to periodical 2018