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Koruza, Jurij (author), Zhang, Mao Hua (author), Hadaeghi, Niloofar (author), Egert, Sonja (author), Ding, Hui (author), Zhang, Hongbin (author), Braga Groszewicz, P. (author), Buntkowsky, Gerd (author), Klein, Andreas (author)Antiferroelectric materials exhibit a unique electric-field-induced phase transition, which enables their use in energy storage, electrocaloric cooling, and nonvolatile memory applications. However, in many prototype antiferroelectrics this transition is irreversible, which prevents their implementation. In this work, we demonstrate a general...journal article 2020
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Cremers, Lotte G.M. (author), Huizinga, Wyke (author), Niessen, W.J. (author), Krestin, Gabriel P. (author), Poot, D.H.J. (author), Ikram, M. Arfan (author), Lötjönen, Jyrki (author), Klein, S. (author), Vernooij, Meike W. (author)Background: Identifying persons at risk for cognitive decline may aid in early detection of persons at risk of dementia and to select those that would benefit most from therapeutic or preventive measures for dementia. Objective: In this study we aimed to validate whether cognitive decline in the general population can be predicted with...journal article 2020
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Del Grosso, M. (author), Sridharan, Balaji (author), Tsekos, C. (author), Klein, S.A. (author), de Jong, W. (author)This work is focused on the process system modelling of an indirectly heated gasifier (10 MW<sub>th</sub>) using torrefied wood as feedstock and its integration with methanol and power production using Aspen Plus®. The modelling of the gasification process along with the obtained reaction kinetics were validated with experimental data found...journal article 2020
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Xiberras, Joeline (author), Klein, Mathias (author), de Hulster, A.F. (author), Mans, R. (author), Nevoigt, Elke (author)Previously, our lab replaced the endogenous FAD-dependent pathway for glycerol catabolism in S. cerevisiae by the synthetic NAD-dependent dihydroxyacetone (DHA) pathway. The respective modifications allow the full exploitation of glycerol’s higher reducing power (compared to sugars) for the production of the platform chemical succinic acid ...journal article 2020
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van Valenberg, W. (author), Klein, S. (author), Vos, F.M. (author), Koolstra, Kirsten (author), van Vliet, L.J. (author), Poot, D.H.J. (author)Quantitative MRI methods that estimate multiple physical parameters simultaneously often require the fitting of a computational complex signal model defined through the Bloch equations. Repeated Bloch simulations can be avoided by matching the measured signal with a precomputed signal dictionary on a discrete parameter grid (i.e. lookup table...journal article 2020
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Timbergen, Milea J.M. (author), Starmans, Martijn P.A. (author), Padmos, Guillaume A. (author), Grünhagen, Dirk J. (author), van Leenders, Geert J.L.H. (author), Hanff, D. F. (author), Niessen, W.J. (author), Klein, S. (author), Visser, J.J. (author)Purpose: Diagnosing desmoid-type fibromatosis (DTF) requires an invasive tissue biopsy with β-catenin staining and CTNNB1 mutational analysis, and is challenging due to its rarity. The aim of this study was to evaluate radiomics for distinguishing DTF from soft tissue sarcomas (STS), and in DTF, for predicting the CTNNB1 mutation types....journal article 2020
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Felimban, Ahmed Abdulazeem (author), Prieto Hoces, A.I. (author), Knaack, U. (author), Klein, T. (author), Qaffas, Yasser (author)In the Kingdom of Saudi Arabia (KSA), residential buildings' energy consumption accounts for almost 50% of the building stock electricity consumption. The KSA's economy relies heavily on fossil fuel sources, namely oil reservoirs, whose depletion will negatively affect the future development of the country. The total electricity consumption is...journal article 2019
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Venkatraghavan, Vikram (author), Bron, Esther E. (author), Niessen, W.J. (author), Klein, S. (author)Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in which biomarkers for a disease become abnormal based on cross-sectional data. It can help in understanding...journal article 2019
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Gangoli Rao, A. (author), van den Oudenalder, F. S.C. (author), Klein, S.A. (author)The energy scenario is currently undergoing a rapid transition in the pursuit of increasing the share of renewable energy sources in order to reduce the global anthropogenic CO2 emission. However, since several of the renewable energy sources are intermittent in nature, like wind and solar, this intermittency gives rise to several problems in...journal article 2019
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Klein, Martin (author), Ziade, Ahmad (author), De Vries, Laurens (author)PV-battery systems are currently not operated in an energy system optimal way as their operation heuristic (maximization of self-consumption) is generally unaffected by competitive market signals. To evaluate potential regulatory intervention, we propose a market alignment indicator which measures the relative economic efficiency of a prosumer...journal article 2019
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Cui, Thijs (author), Klein, M. (author), Hegge, Jorrit W. (author), Chandradoss, S.D. (author), van der Oost, John (author), Depken, S.M. (author), Joo, C. (author)Argonaute (Ago) proteins are key players in both gene regulation (eukaryotes) and host defense (prokaryotes). Acting on single-stranded nucleic-acid substrates, Ago relies on base pairing between a small nucleic-acid guide and its complementary target sequences for specificity. To efficiently scan nucleic-acid chains for targets, Ago diffuses...journal article 2019
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Klein, Patrick (author), van der Vegte, Wilhelm Frederik (author), Hribernik, Karl (author), Klaus-Dieter, Thoben (author)By applying data analytics to product usage information (PUI) from combinations of different channels, companies can get a more complete picture of their products' and services' Mid-Of-Life. All data, which is gathered within the usage phase of a product and which relates to a more comprehensive understanding of the usability of the product...journal article 2019
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Lauth, J.D. (author), Failla, M. (author), Klein, Eugen (author), Klinke, Christian (author), Kinge, S.S. (author), Siebbeles, L.D.A. (author)Solution-processable two-dimensional (2D) semiconductors with chemically tunable thickness and associated tunable band gaps are highly promising materials for ultrathin optoelectronics. Here, the properties of free charge carriers and excitons in 2D PbS nanosheets of different thickness are investigated by means of optical pump-terahertz...journal article 2019
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Vinke, Elisabeth J. (author), de Groot, Marius (author), Venkatraghavan, Vikram (author), Klein, S. (author), Niessen, W.J. (author), Ikram, M. Arfan (author), Vernooij, Meike W. (author)With aging, the brain undergoes several structural changes. These changes reflect the normal aging process and are therefore not necessarily pathologic. In fact, better understanding of these normal changes is an important cornerstone to also disentangle pathologic changes. Several studies have investigated normal brain aging, both cross...journal article 2018
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Azcarate Aguerre, J.F. (author), Klein, T. (author), den Heijer, A.C. (author), Vrijhoef, R. (author), Ploeger, H.D. (author), Prins, M. (author)The construction and renovation of the building envelope represents a significant fraction of a project’s life-cycle costs. It also has a determinant effect on the potential reduction in energy use, as well as on the improvement of the building’s indoor comfort. Nevertheless, the challenge of a low rate and depth in building energy renovations...journal article 2018
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Prieto Hoces, A.I. (author), Knaack, U. (author), Auer, Thomas (author), Klein, T. (author)Cooling demands of commercial buildings present a relevant challenge for a sustainable future. They account for over half of the overall energy needs for the operation of an average office building in warm climates, and this situation is expected to become more pressing due to increasing temperatures in cities worldwide. To tackle this issue, it...journal article 2018
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Suárez, Rafael (author), Escandon, R. (author), López-Pérez, Ramón (author), León-Rodríguez, Ángel Luis (author), Klein, T. (author), Silvester, S. (author)According to the IPCC Climate Change projections by 2050 temperatures in southern Spain will have increased noticeably during the summer. Housing-in its current form-will not be able to provide a suitable response to this new climate scenario, and will in turn prompt an increase in cooling energy consumption and a series of problems relating...journal article 2018
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Vimalakanthan, K. (author), Schepers, J.G. (author), Shen, W. Z. (author), Rahimi, H. (author), Micallef, D. (author), Ferreira, Carlos (author), Jost, E. (author), Klein, L. (author)As part of the AVATAR and Mexnext projects, this study compares several methods used to derive lifting line variables from CFD simulations of the MEXICO rotor in yawed inflow. The results from six partners within the AVATAR/Mexnext consortium using five different methods of extraction were compared. Overall comparison of the induced...journal article 2018
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Prieto Hoces, A.I. (author), Knaack, U. (author), Auer, Thomas (author), Klein, T. (author)Small-scale systems and integrated concepts are currently being explored to promote the widespread application of solar cooling technologies in buildings. This article seeks to expand application possibilities by exploring the feasibility of solar cooling integrated façades, as decentralized self-sufficient cooling modules on different warm...journal article 2018
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Polfliet, Mathias (author), Klein, S. (author), Huizinga, W. (author), Paulides, Margarethus M. (author), Niessen, W.J. (author), Vandemeulebroucke, Jef (author)Image registration is an important task in medical image analysis. Whereas most methods are designed for the registration of two images (pairwise registration), there is an increasing interest in simultaneously aligning more than two images using groupwise registration. Multimodal registration in a groupwise setting remains difficult, due to...journal article 2018