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Morgana, Florencia (author), Opstelten, Rianne (author), Slot, Manon C. (author), Scott, Andrew M. (author), van Lier, René A.W. (author), Blom, Bianca (author), Mahfouz, A.M.E.T.A. (author), Amsen, Derk (author)CD4+CD25+FOXP3+ regulatory T (Treg) cells control immunological tolerance. Treg cells are generated in the thymus (tTreg) or in the periphery. Their superior lineage fidelity makes tTregs the preferred cell type for adoptive cell therapy (ACT). How human tTreg cells develop is incompletely understood. By combining single-cell transcriptomics...journal article 2022