Synergistic effects of cerium-containing bioactive glasses and apoptotic extracellular vesicles alleviate bisphosphonate-related osteonecrosis of jaw

Bisphosphonates (BPs) are commonly used to treat skeletal diseases. However, long-term use of BPs can lead to BP-related jaw bone necrosis (BRONJ), particularly in patients undergoing tooth extraction surgery. The treatment of BRONJ remains challenging due to the local inflammatory microenvironment. To address this issue, we developed...

Impacts of urban morphology on sensible heat flux and net radiation exchange

Urban morphology affects the sensible heat flux and net radiation exchange which can alter urban heat mitigation plans. This study first parameterized the geometric effects on the net radiation, and then calculated the net radiation and sensible heat flux in the urban landscape of Hong Kong. Considering that the sensible heat flux is the main...

Characterizing the thermal effects of vegetation on urban surface temperature

Vegetation is important for urban heat mitigation. The cooling intensity of vegetation is affected by background climate and urban design. How to evaluate vegetation cooling efficiency under different climate conditions is still an issue open to discussion. In this study, a normalized indicator of urban vegetation cooling efficiency (NVCE) is...

Changjiang Delta in the Anthropocene: Multi-scale hydro-morphodynamics and management challenges

The Changjiang Delta (CD) is one of well-studied large deltas of critical socio-economical and ecological importance regionally and global representativeness. Cumulated field data and numerical modeling has facilitated scientific understanding of its hydro-morphodynamics at multiple spatial and time scales, but the changing boundary forcing...