- document
-
Kolken, H.M.A. (author), Garcia, A. Fontecha (author), Du Plessis, A. (author), Rans, C.D. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Meta-biomaterials offer a promising route towards the development of life-lasting implants. The concept aims to achieve solutions that are ordinarily impossible, by offering a unique combination of mechanical, mass transport, and biological properties through the optimization of their small-scale geometrical and topological designs. In this...journal article 2021
- document
-
Oldhoff, M. G.E. (author), Mirzaali, Mohammad J. (author), Tümer, N. (author), Zhou, J. (author), Zadpoor, A.A. (author)Additive manufacturing (AM) offers great design freedom that enables objects with desired unique and complex geometry and topology to be readily and cost-effectively fabricated. The overall benefits of AM are well known, such as increased material and resource efficiency, enhanced design and production flexibility, the ability to create...journal article 2021
- document
-
van Hengel, I.A.J. (author), Lacin, M. (author), Minneboo, M.B. (author), Fratila-Apachitei, E.L. (author), Apachitei, I. (author), Zadpoor, A.A. (author)Surface biofunctionalization is frequently applied to enhance the functionality and longevity of orthopedic implants. Here, we investigated the osteogenic effects of additively manufactured porous Ti6Al4V implants whose surfaces were biofunctionalized using plasma electrolytic oxidation (PEO) in Ca/P-based electrolytes with or without...journal article 2021
- document
-
Polozov, Igor (author), Kantyukov, Artem (author), Starikov, Kirill (author), Gracheva, Anna (author), Popovich, V. (author), Popovich, Anatoly (author)Titanium aluminide alloys are considered to be attractive materials for aerospace and automotive high-temperature applications due to their high specific strength, creep resistance, and heat resistance. However, their brittleness makes it difficult to manufacture complex-shaped components of these alloys using conventional processes making...conference paper 2021
- document
-
Borisov, Evgenii (author), Starikov, Kirill (author), Kim, Artem (author), Popovich, V. (author), Popovich, Anatoly (author)The aim of this study was to determine the influence of heat treatment on the microstructure of single-crystal nickel-based alloy manufactured by selective laser melting with a high-temperature substrate preheating. The change of gamma/gamma prime -phases ratio was established as a result of various heat treatment modes.conference paper 2021
- document
-
Boon, W.P.C. (author), van Wee, G.P. (author)3D printing (3DP) is an emerging technology associated with a more tailor-made, distributed way of manufacturing which, if successful, is bound to have repercussions on transport, supply chains, and logistics. This contribution delves into what 3DP is, how it will influence consumer wants and needs, location choices and transport resistance, and...book chapter 2021
- document
-
Li, Y. (author), Jahr, H. (author), Zhou, J. (author), Zadpoor, A.A. (author)Partially due to the unavailability of ideal bone substitutes, the treatment of large bony defects remains one of the most important challenges of orthopedic surgery. Additively manufactured (AM) biodegradable porous metals that have emerged since 2018 provide unprecedented opportunities for fulfilling the requirements of an ideal bone...review 2020
- document
-
Fleischer, J.C. (author), Diehl, J.C. (author), Wauben, L.S.G.L. (author), Dankelman, J. (author)Three-dimensional (3D) printing may be a solution to shortages of equipment and spare parts in the healthcare sector of low- and middle-income countries (LMICs). Polylactic acid (PLA) for 3D printing is widely available and biocompatible, but there is a gap in knowledge concerning its compatibility with chemical disinfectants. In this study, 3D...journal article 2020
- document
-
Kolken, H.M.A. (author), Lietaert, K. (author), van der Sloten, T. (author), Pouran, B. (author), Meynen, A. (author), Van Loock, G. (author), Weinans, Harrie (author), Scheys, L. (author), Zadpoor, A.A. (author)The innovative design of orthopedic implants could play an important role in the development of life-lasting implants, by improving both primary and secondary implant fixations. The concept of meta-biomaterials aims to achieve a unique combination of mechanical, mass transport, and biological properties through optimized topological design of...journal article 2020
- document
-
van Hengel, I.A.J. (author), Gelderman, F. S.A. (author), Athanasiadis, S. (author), Minneboo, M.B. (author), Weinans, Harrie (author), Fluit, A. C. (author), van der Eerden, B.C.J. (author), Fratila-Apachitei, E.L. (author), Apachitei, I. (author), Zadpoor, A.A. (author)The holy grail of orthopedic implant design is to ward off both aseptic and septic loosening for long enough that the implant outlives the patient. Questing this holy grail is feasible only if orthopedic biomaterials possess a long list of functionalities that enable them to discharge the onerous task of permanently replacing the native bone...journal article 2020
- document
-
van de Ven, E.A. (author), Maas, Robert (author), Ayas, C. (author), Langelaar, Matthijs (author), van Keulen, A. (author)It is attractive to combine topology optimization (TO) with additive manufacturing (AM), due to the design freedom provided by AM, and the increased performance that can be achieved with TO. One important aspect is to include the design rules associated with the process restrictions of AM to prevent the requirement of relatively large support...journal article 2020
- document
-
Putra, N.E. (author), Mirzaali, Mohammad J. (author), Apachitei, I. (author), Zhou, J. (author), Zadpoor, A.A. (author)The growing interest in multi-functional metallic biomaterials for bone substitutes challenges the current additive manufacturing (AM, =3D printing) technologies. It is foreseeable that advances in multi-material AM for metallic biomaterials will not only allow for complex geometrical designs, but also improve their multi-functionalities by...review 2020
- document
-
van Hengel, I.A.J. (author), Putra, N.E. (author), Tierolf, M. W.A.M. (author), Minneboo, M.B. (author), Fluit, A. C. (author), Fratila-Apachitei, E.L. (author), Apachitei, I. (author), Zadpoor, A.A. (author)Antibiotic-resistant bacteria are frequently involved in implant-associated infections (IAIs), making the treatment of these infections even more challenging. Therefore, multifunctional implant surfaces that simultaneously possess antibacterial activity and induce osseointegration are highly desired in order to prevent IAIs. The incorporation...journal article 2020
- document
-
Kuipers, T. (author), Doubrovski, E.L. (author), Wu, J. (author), Wang, C.C. (author)3D printing techniques such as Fused Deposition Modeling (FDM) have enabled the fabrication of complex geometry quickly and cheaply. Objects are produced by filling (a portion of) the 2D polygons of consecutive layers with contour-parallel extrusion toolpaths. Uniform width toolpaths consisting of inward offsets from the outline polygons...journal article 2020
- document
-
Karami, K. (author), Blok, A. (author), Weber, L.R.M. (author), Ahmadi, S.M. (author), Petrov, R.H. (author), Nikolic, Ksenija (author), Borisov, E.V. (author), Leeflang, M.A. (author), Ayas, C. (author), Zadpoor, A.A. (author), Mehdipour, M. (author), Reinton, T.E. (author), Popovich, V. (author)Additive manufacturing technologies in general and laser powder bed fusion (L-PBF) in particular have been on the rise in different applications, including biomedical implants. The effects of the various L-PBF process parameters on the microstructure and properties of Ti6Al4V lattice structures have been studied before. However, the...journal article 2020
- document
-
Sobota, V.C.M. (author), van de Kaa, G. (author), Luomaranta, Toni (author), Martinsuo, Miia (author), Ortt, J.R. (author)Purpose: This paper addresses the most important factors for the selection of additive manufacturing (AM) technology as a method of production of metal parts. AM creates objects by adding material layer by layer based on 3D models. At present, interest in AM is high as it is hoped that AM contributes to the competitiveness of Western...journal article 2020
- document
-
Li, Y. (author), Pavanram, P. (author), Zhou, J. (author), Lietaert, K. (author), Taheri, P. (author), Li, W. (author), San, H. (author), Leeflang, M.A. (author), Mol, J.M.C. (author), Jahr, H. (author), Zadpoor, A.A. (author)Additively manufacturing (AM) opens up the possibility for biodegradable metals to possess uniquely combined characteristics that are desired for bone substitution, including bone-mimicking mechanical properties, topologically ordered porous structure, pore interconnectivity and biodegradability. Zinc is considered to be one of the promising...journal article 2020
- document
-
Dong, J. (author), Li, Y. (author), Lin, P. (author), Leeflang, M.A. (author), van Asperen, S. (author), Yu, K. (author), Tümer, N. (author), Norder, B. (author), Zadpoor, A.A. (author), Zhou, J. (author)Biodegradable porous magnesium (Mg) scaffolds are promising for application in the regeneration of critical-sized bone defects. Although additive manufacturing (AM) carries the promise of offering unique opportunities to fabricate porous Mg scaffolds, current attempts to apply the AM approach to fabricating Mg scaffolds have encountered some...journal article 2020
- document
-
Kies, Fabian (author), Ikeda, Yuji (author), Ewald, Simon (author), Schleifenbaum, Johannes H. (author), Hallstedt, Bengt (author), Körmann, F.H.W. (author), Haase, Christian (author)Density functional theory (DFT) calculations were performed on Al<sub>x</sub>C<sub>y</sub>CoFeMnNi multi-principal element alloys (MPEAs) to understand the influence of Al and C on the stacking-fault energy (SFE). C addition to CoFeMnNi resulted in increased SFE, while it decreased in Al-alloyed CoFeMnNi. For experimental verification, Al<sub...journal article 2020
- document
-
Polozov, Igor (author), Kantyukov, Artem (author), Goncharov, Ivan (author), Razumov, Nikolay (author), Silin, Alexey (author), Popovich, V. (author), Zhu, Jia-Ning (author), Popovich, Anatoly (author)In this paper, laser powder-bed fusion (L-PBF) additive manufacturing (AM) with a high-temperature inductive platform preheating was used to fabricate intermetallic TiAl-alloy samples. The gas atomized (GA) and mechanically alloyed plasma spheroidized (MAPS) powders of the Ti-48Al-2Cr-2Nb (at. %) alloy were used as the feedstock material. The...journal article 2020