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Van den Eynde, Jef (author), Westenberg, Jos J.M. (author), Hazekamp, Mark G. (author), Lamb, Hildo J. (author), Jongbloed, Monique R.M. (author), Wentzel, Jolanda J. (author), Kenjeres, S. (author), Dekkers, Ilona A. (author), Rijnberg, F.M. (author)
BACKGROUND: Kidney disease is the most important predictor of death in patients with a Fontan circulation, yet its clinical and hemodynamic correlates have not been well established. METHODS AND RESULTS: A total of 53 ambulatory patients with a Fontan circulation (median age, 16.2 years, 52.8% male patients) underwent advanced cardiovascular...
journal article 2024
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van der Jagt, T.F.W. (author), Jongbloed, G. (author), Vittorietti, M. (author)
Consider an opaque medium that contains 3D particles. All particles are convex bodies of the same shape, but they vary in size. The particles are randomly positioned and oriented within the medium and cannot be observed directly. Taking a planar section of the medium we obtain a sample of observed 2D section profile areas of the intersected...
journal article 2024
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Hut, T.Y. (author), Roest, Arno (author), Gaillard, D.H.K. (author), Hazekamp, Mark (author), Van Den Boogaard, Pieter (author), Lamb, Hildo (author), Jongbloed, Monique (author), Rijnberg, Friso (author), Kenjeres, S. (author)
Objectives: Recent evidence suggests that conduits implanted in Fontan patients at the age of 2-4 years become undersized for adulthood. The objective of this study is to use computational fluid dynamic models to evaluate the effect of virtual expansion of the Fontan conduit on haemodynamics and energetics of the total cavopulmonary...
journal article 2023
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van der Jagt, T.F.W. (author), Jongbloed, G. (author), Vittorietti, M. (author)
In various stereological problems ann-dimensional convex body is intersected with an(n−1)-dimensionalIsotropic Uniformly Random (IUR) hyperplane. In this paper the cumulative distribution function associatedwith the(n−1)-dimensional volume of such a random section is studied. This distribution is also knownas chord length distribution and cross...
journal article 2023
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Jongbloed, Elisabeth M. (author), Jansen, Maurice P.H.M. (author), de Weerd, Vanja (author), Helmijr, Jean A. (author), Beaufort, Corine M. (author), Reinders, M.J.T. (author), van Marion, Ronald (author), van IJcken, Wilfred F.J. (author), Makrodimitris, S. (author)
Next generation sequencing of cell-free DNA (cfDNA) is a promising method for treatment monitoring and therapy selection in metastatic breast cancer (MBC). However, distinguishing tumor-specific variants from sequencing artefacts and germline variation with low false discovery rate is challenging when using large targeted sequencing panels...
journal article 2023
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Ciszewski, M.G. (author), Söhl, J. (author), Jongbloed, G. (author)
The past decade has seen an increased interest in human activity recognition based on sensor data. Most often, the sensor data come unannotated, creating the need for fast labelling methods. For assessing the quality of the labelling, an appropriate performance measure has to be chosen. Our main contribution is a novel post-processing method...
journal article 2023
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Rijnberg, Friso M. (author), van ‘t Hul, Luca C. (author), Hazekamp, Mark G. (author), van den Boogaard, Pieter J. (author), Juffermans, Joe F. (author), Lamb, Hildo J. (author), Kenjeres, S. (author), le Cessie, Saskia (author), Jongbloed, Monique R.M. (author)
OBJECTIVES: To date, it is not known if 16–20-mm extracardiac conduits are outgrown during somatic growth from childhood to adolescence. This study aims to determine total cavopulmonary connection (TCPC) haemodynamics in adolescent Fontan patients at rest and during simulated exercise and to assess the relationship between conduit size and...
journal article 2023
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Jongbloed, B.C.P. (author), Teuwen, Julie J.E. (author), Villegas, I.F. (author)
Continuous ultrasonic welding is an attractive welding technique for thermoplastic composite structures. In this process, a metallic sonotrode connected to a piezoelectric transducer and to a press moves along the parts to be welded applying ultrasonic vibrations and a static welding force on the welding overlap. Thus far, the research carried...
journal article 2023
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Mészáros, L. (author), van der Meulen, F.H. (author), Jongbloed, G. (author), El Serafy, G.Y.H. (author)
Coastal climate impact studies make increasing use of multi-source and multi-dimensional atmospheric and environmental datasets to investigate relationships between climate signals and the ecological response. The large quantity of numerically simulated data may, however, include redundancy, multi-colinearity and excess information not relevant...
journal article 2022
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Vittorietti, M. (author), Hidalgo Garcia, J. (author), Galan Lopez, J. (author), Sietsma, J. (author), Jongbloed, G. (author)
This study proposes a new approach to determine phenomenological or physical relations between microstructure features and the mechanical behavior of metals bridging advanced statistics and materials science in a study of the effect of hard precipitates on the hardening of metal alloys. Synthetic microstructures were created using multi-level...
journal article 2022
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el Bouhaddani, Said (author), Uh, Hae Won (author), Jongbloed, G. (author), Houwing-Duistermaat, Jeanine (author)
The availability of multi-omics data has revolutionized the life sciences by creating avenues for integrated system-level approaches. Data integration links the information across datasets to better understand the underlying biological processes. However, high dimensionality, correlations and heterogeneity pose statistical and computational...
journal article 2022
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Velthoen, J.J. (author), Cai, Juan Juan (author), Jongbloed, G. (author)
Random forest is a popular prediction approach for handling high dimensional covariates. However, it often becomes infeasible to interpret the obtained high dimensional and non-parametric model. Aiming for an interpretable predictive model, we develop a forward variable selection method using the continuous ranked probability score (CRPS) as...
journal article 2022
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Jongbloed, B.C.P. (author), Vinod, R. (author), Teuwen, Julie J.E. (author), Benedictus, R. (author), Villegas, I.F. (author)
Continuous ultrasonic welding is a promising high-speed and energy-efficient joining technique for thermoplastic composite structures. However, in the current state-of-the-art research on the topic numerous deconsolidation voids could be identified at the welding interface, which results in a strength knock-down. The aim of this study is,...
journal article 2022
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Rijnberg, Friso M. (author), van der Woude, S.F.S. (author), Hazekamp, Mark G. (author), Van Den Boogaard, Pieter J. (author), Lamb, Hildo J. (author), Terol Espinosa De Los Monteros, Covadonga (author), Kenjeres, S. (author), Karim, Tawab (author), Jongbloed, Monique R.M. (author)
OBJECTIVES: Adequacy of 16-20mm extracardiac conduits for adolescent Fontan patients remains unknown. This study aims to evaluate conduit adequacy using the inferior vena cava (IVC)-conduit velocity mismatch factor along the respiratory cycle. METHODS: Real-time 2D flow MRI was prospectively acquired in 50 extracardiac (16-20mm conduits)...
journal article 2022
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Jongbloed, Hendrik (author), Schuttelaars, H.M. (author), Dijkstra, Y.M. (author), Donkers, Paul B. (author), Hoitink, Antonius J.F. (author)
An idealized width-averaged model is employed to study the influence of wind stress on subtidal salt intrusion and stratification in well-mixed and partially stratified estuaries. We show that even in mild conditions, wind forcing can influence the estuarine salinity structure in a substantial way. By studying the role of wind forcing on...
journal article 2022
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Mészáros, L. (author), van der Meulen, F.H. (author), Jongbloed, G. (author), El Serafy, G.Y.H. (author)
Spring phytoplankton blooms in the southern North Sea substantially contribute to annual primary production and largely influence food web dynamics. Studying long-term changes in spring bloom dynamics is therefore crucial for understanding future climate responses and predicting implications on the marine ecosystem. This paper aims to study...
journal article 2021
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Jongbloed, B.C.P. (author), Teuwen, Julie J.E. (author), Benedictus, R. (author), Villegas, I.F. (author)
Continuous ultrasonic welding is a promising technique for joining thermoplastic composites structures together. The aim of this study was to gain further insight into what causes higher through-the-thickness heating in continuous ultrasonic welding of thermoplastic composites as compared to the static process. Thermocouples were used to measure...
journal article 2021
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Vittorietti, M. (author), Hidalgo Garcia, J. (author), Sietsma, J. (author), Li, W. (author), Jongbloed, G. (author)
Investigating the main determinants of the mechanical performance of metals is not a simple task. Already known physically inspired qualitative relations between 2D microstructure characteristics and 3D mechanical properties can act as the starting point of the investigation. Isotonic regression allows to take into account ordering relations...
journal article 2021
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Li, W. (author), Vittorietti, M. (author), Jongbloed, G. (author), Sietsma, J. (author)
Abstract: The relationship between microstructure features and mechanical properties plays an important role in the design of materials and improvement of properties. Hole expansion capacity plays a fundamental role in defining the formability of metal sheets. Due to the complexity of the experimental procedure of testing hole expansion...
journal article 2021
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Jongbloed, G. (author), van der Meulen, F.H. (author), Pang, L. (author)
We consider the current status continuous mark model where, if an event takes place before an inspection time T a “continuous mark” variable is observed as well. A Bayesian nonparametric method is introduced for estimating the distribution function of the joint distribution of the event time (X) and mark variable (Y). We consider two...
journal article 2021
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