Assessment Method for Spatial Planning and Infrastructure Development

In Europe, different road authorities have to face the ever increasing pressure to integrate their road network service provision with - often conflicting - different trends and conditions such as congestion, climate change, individualism, urbanization, safety, environmental issues and economic growth. There is also a need to cooperate with...

Analysis of in competition speed skating using IMU's

For feedback to be effective, we must first identify relevant performance indicators for speed skating. We instrumented the skating of 10 junior elite Dutch speed skaters with two inertial measurement units during two competition events. Contact time, stroke frequency and other parameters were derived from collected IMU data and related to...

A sensitivity analysis of freight transport forecasts for The Netherlands

Strategic freight transport models can be used for a quantitative analysis of long term forecasts. This paper discusses an analysis of the bandwidth of freight transport forecasts for The Netherlands with the strategic freight transport model ‘BasGoed’. This model was developed over the past years as a basic model, satisfying the needs of policy...

An LCA-based evaluation of biomass to transportation fuel production and utilization pathways in a large port’s context

This study evaluates whether a transition of large ports facilities to biofuel production for mobility improves the environmental performance and satisfies the renewable energy directive (RED) and it is the first LCA study that considers biofuel production from torrefied wood. The systems studied are wood, torrefied wood, and straw pellets...

Pilot scale steam-oxygen CFB gasification of commercial torrefied wood pellets. The effect of torrefaction on the gasification performance

Torrefaction is a promising biomass upgrading technology as it makes biomass more coal alike and offers benefits in logistics and handling operations. Gasification is an attractive thermochemical conversion technology due to its flexibility in the product gas end-uses. Therefore, it is valuable to investigate whether additional benefits are...

The effect of torrefaction on the process performance of oxygen-steam blown CFB gasification of hardwood and softwood

Torrefaction is a promising biomass upgrading method, offering advantages in logistics and handling. Gasification is an attractive thermochemical conversion technology due to its flexibility in the product gas end-use. The aim of this paper is to investigate the impact of torrefaction on the gasification performance of a softwood (spruce) and...

Toepassing Afweegmethode voor Benutten op vier cases

Een integrale afweegmethode voor benutten

Voor het beoordelen van maatregelen en het samenstellen van maatregelpakketten met een focus op benutting, zijn diverse methoden en tools beschikbaar. Deze methoden zijn vooral werkwijzen of stappenplannen om op regionaal niveau te komen tot, door alle betrokken partijen gedragen, pakketten van benuttingsmaatregelen. Deze methoden kennen allen...

What big data do not tell us: What we can learn from travel survey for bus and lightrail in the Netherlands

With the introduction of the chipcardfor public transport (OV-chipkaart) as a digital ticketing system in the Dutch public transport (PT), a new data source for PT was created. The data registered by this smartcard contain every transaction (check-ins and check-outs) with according time and location. In 2013, the OV-chipkaart system operator...

Identification of promising Twin Hub networks: Report of Work Package 1 of the Intermodal rail freight Twin hub Network Northwest Europe - project (final report)

This report is the first deliverable of the project Intermodal Rail Freight Twin Hub Network Northwest Europe. We call its subject Twin hub network and the organisational entity to carry out the actions the Twin hub project. The project is funded by INTERREG NWE (programme IVb). Its work started in December 2011 and will end by the end of 2015....

Metabolic engineering of ?-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis

Industrial production of semi-synthetic cephalosporins by Penicillium chrysogenum requires supplementation of the growth media with the side-chain precursor adipic acid. In glucose-limited chemostat cultures of P. chrysogenum, up to 88% of the consumed adipic acid was not recovered in cephalosporin-related products, but used as an additional...

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach

Background In microbial production of non-catabolic products such as antibiotics a loss of production capacity upon long-term cultivation (for example chemostat), a phenomenon called strain degeneration, is often observed. In this study a systems biology approach, monitoring changes from gene to produced flux, was used to study degeneration of...

An Engineered Yeast Efficiently Secreting Penicillin

This study aimed at developing an alternative host for the production of penicillin (PEN). As yet, the industrial production of this β-lactam antibiotic is confined to the filamentous fungus Penicillium chrysogenum. As such, the yeast Hansenula polymorpha, a recognized producer of pharmaceuticals, represents an attractive alternative....

Production of functionally active Penicillium chrysogenum isopenicillin N synthase in the yeast Hansenula polymorpha

Background: ?-Lactams like penicillin and cephalosporin are among the oldes known antibiotics used against bacterial infections. Industrially, penicillin is produced by the filamentous fungus Penicillium chrysogenum. Our goal is to introduce the entire penicillin biosynthesis pathway into the methylotrophic yeast Hansenula polymorpha. Yeast...

Metaalcomplexen van alizarinerood (1,2-dihydroxyanthrachinon)

Phenol uit cumeen

Document(en) uit de collectie Chemische Procestechnologie