Combined Chemoradionuclide Therapy Using Poly(ε-caprolactone-b-ethylene oxide) Micelles as the Delivery Vehicle

Combination of therapies is a common strategy in cancer treatment. Such combined therapies only have merit provided that there is superior therapeutic outcome with fewer side effects, compared to single therapies. Here, this work explores the possibility to combine chemotherapy with radionuclide therapy using polymeric micelles as a delivery...

Field measurements and numerical modelling of wind-driven exchange flows in a tidal inlet system in the Dutch Wadden Sea

Multiple tidal inlet systems like the Wadden Sea have long been considered as separated basins, bordered by so-called tidal divides. Recently, it was however shown that fluxes of water and sediment occur over the borders of these basins, especially during wind events. In this paper, the wind-driven fluxes over these borders and the residual...