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van der Vos, K.E. (author), Vis, D.J. (author), Nevedomskaya, E. (author), Kim, Y. (author), Choi, W. (author), McConkey, D. (author), Wessels, L.F.A. (author), van Rhijn, B.W.G. (author), Zwart, W. (author), van der Heijden, M.S. (author)
Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease that often recurs despite aggressive treatment with neoadjuvant chemotherapy and (radical) cystectomy. Basal and luminal molecular subtypes have been identified that are linked to clinical characteristics and have differential sensitivities to chemotherapy. While it has been...
journal article 2020
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Singh, Abhishek A. (author), Schuurman, Karianne (author), Nevedomskaya, Ekaterina (author), Stelloo, Suzan (author), Linder, Simon (author), Droog, Marjolein (author), Kim, Yongsoo (author), Sanders, Joyce (author), van der Poel, Henk (author), Bergman, Andries M. (author), Wessels, L.F.A. (author), Zwart, Wilbert (author)
Chromatin immunoprecipitation (ChIP)-seq analyses of transcription factors in clinical specimens are challenging due to the technical limitations and low quantities of starting material, often resulting in low enrichments and poor signal-to-noise ratio. Here, we present an optimized protocol for transcription factor ChIP-seq analyses in human...
journal article 2019