- document
-
Marien, Eyra (author), Meister, Michael (author), Muley, Thomas (author), del Pulgar, Teresa Gomez (author), Derua, Rita (author), Spraggins, Jeffrey M. (author), Van de Plas, Raf (author), Vanderhoydonc, Frank (author), Machiels, Jelle (author), Binda, Maria Mercedes (author), Dehairs, Jonas (author), Willette-Brown, Jami (author), Hu, Yinling (author), Dienemann, Hendrik (author), Thomas, Michael (author), Schnabe, Philipp A. (author), Caprioli, Richard M. (author), Lacal, Juan Carlos (author), Waelkens, Etienne (author), Swinnen, Johannes V. (author)Lung cancer is the leading cause of cancer death. Beyond first line treatment, few therapeutic options are available, particularly for squamous cell carcinoma (SCC). Here, we have explored the phospholipidomes of 30 human SCCs and found that they almost invariably (in 96.7% of cases) contain phospholipids with longer acyl chains compared to...journal article 2016
- document
-
Marien, E. (author), Meister, M. (author), Muley, T. (author), Fieuws, S. (author), Bordel, S. (author), Derua, R. (author), Spraggins, J. (author), Van de Plas, R. (author), Dehairs, J. (author), Wouters, J. (author), Bagadi, M. (author), Dienemann, H. (author), Thomas, M. (author), Schnabel, P.A. (author), Caprioli, R.M. (author), Waelkens, E. (author), Swinnen, J.V. (author)Non-small cell lung cancer (NSCLC) is the leading cause of cancer death globally. To develop better diagnostics and more effective treatments, research in the past decades has focused on identification of molecular changes in the genome, transcriptome, proteome, and more recently also the metabolome. Phospholipids, which nevertheless play a...journal article 2015