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Laan, A.C. (author), Santini, Costanza (author), Jennings, Laurence (author), de Jong, Marion (author), Bernsen, Monique R. (author), Denkova, A.G. (author)Background: Single photon emission computed tomography (SPECT) is an indispensable tool in the determination of the in vivo fate of polymeric micelles. However, for this purpose, the micelles need to be radiolabeled, and almost all radiolabeling procedures published to date involve the conjugation of a chelating agent to the constituting...journal article 2016
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Arranja, Alexandra (author), Ivashchenko, O. (author), Denkova, A.G. (author), Morawska, K.M. (author), Van Vlierberghe, Sandra (author), Dubruel, Peter (author), Waton, Gilles (author), Beekman, F.J. (author), Schosseler, François (author), Mendes, E. (author)Optimal biodistribution and prolonged circulation of nanocarriers improve diagnostic and therapeutic effects of enhanced permeability and retention-based nanomedicines. Despite extensive use of Pluronics in polymer-based pharmaceuticals, the influence of different poly(ethylene oxide) (PEO) block length and aggregation state on the...journal article 2016
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Laan, A.C. (author), Santini, C. (author), Jennings, L. (author), De Jong, M. (author), Bernsen, M.R. (author), Denkova, A.G. (author)Background Single photon emission computed tomography (SPECT) is an indispensable tool in the determination of the in vivo fate of polymeric micelles. However, for this purpose, the micelles need to be radiolabeled, and almost all radiolabeling procedures published to date involve the conjugation of a chelating agent to the constituting polymer,...journal article 2016