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Klijn, F. (author)The policy programme Integrated River Management (IRM) aims to anticipate climate change and to redress the negative consequences of earlier river engineering interventions. Its objective is to first and foremost ensure a well-functioning river system that can provide its essential ‘public’ geo-ecosystem services: safe discharge of floods,...abstract 2024
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George, Bert (author), Klijn, Erik Hans (author), Ropes, Emma (author), Sattlegger, A.S. (author)Collaborative and network governance assume that network management and trust matter for network outcomes. We test this assumption by conducting a meta-analysis of public administration studies investigating the correlation between network management and network outcomes (50 effect sizes), and trust and network outcomes (28 effect sizes)....journal article 2024
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Neijenhuis, T. (author), Le Bussy, Olivier (author), Geldhof, Geoffroy (author), Klijn, M.E. (author), Ottens, M. (author)Protein-based biopharmaceuticals require high purity before final formulation to ensure product safety, making process development time consuming. Implementation of computational approaches at the initial stages of process development offers a significant reduction in development efforts. By preselecting process conditions, experimental...journal article 2024
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Scholte, Mirre (author), Marchau, V.A.W.J. (author), Kwakkel, J.H. (author), Klijn, Catharina J.M. (author), Rovers, Maroeska M. (author), Grutters, Janneke P.C. (author)Objectives: In early stages, the consequences of innovations are often unknown or deeply uncertain, which complicates early health economic modeling (EHEM). The field of decision making under deep uncertainty uses exploratory modeling (EM) in situations when the system model, input probabilities/distributions, and consequences are unknown or...journal article 2022
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Jafino, B.A. (author), Kwakkel, J.H. (author), Klijn, F. (author)To support equitable adaptation planning, quantitative assessments should consider the fairness of the distribution of outcomes to different people. What constitutes a fair distribution, however, is a normative question. In this study, we explore the use of different moral principles drawn from theories of distributive justice to evaluate...journal article 2022
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Ciullo, A. (author), Domeneghetti, A. (author), Kwakkel, J.H. (author), De Bruijn, K. M. (author), Klijn, F. (author), Castellarin, A. (author)Robust Decision Making (RDM) is an established framework for decision making under deep uncertainty. RDM relies on the idea of scenario neutrality, namely that decision robustness is not affected by how scenarios are generated if these are uniformly distributed and span a sufficiently large range of future states of the world. Several authors...journal article 2022
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Klijn, F. (author), Marchand, Marcel (author), Meijer, Karen (author), van der Most, Herman (author), Stuparu, Dana (author)Climate change and socio-economic development result in increasing flood risk which challenges flood risk management policy making and practice. Each situation, however, is different and calls for not only understanding the natural context, but also the socio-economic and cultural context. Only then Flood Risk Management strategies can be...journal article 2021
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Klijn, M.E. (author), Hubbuch, Juergen (author)Imaging is increasingly more utilized as analytical technology in biopharmaceutical formulation research, with applications ranging from subvisible particle characterization to thermal stability screening and residual moisture analysis. This review offers a comprehensive overview of analytical imaging for scientists active in...journal article 2021
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Jafino, B.A. (author), Kwakkel, J.H. (author), Klijn, F. (author), Dung, Nguyen Viet (author), van Delden, Hedwig (author), Haasnoot, Marjolijn (author), Sutanudjaja, Edwin H. (author)The need for explicitly considering equity in climate change adaptation planning is increasingly being recognized. However, evaluations of adaptation often adopt an aggregated perspective, while disaggregation of results is important to learn about who benefits when and where. A typical example is adaptation of rice agriculture in the Vietnam...journal article 2021
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Neves Sao Pedro, M. (author), Klijn, M.E. (author), Eppink, Michel H.M. (author), Ottens, M. (author)The transition to continuous biomanufacturing is considered the next step to reduce costs and improve process robustness in the biopharmaceutical industry, while also improving productivity and product quality. The platform production process for monoclonal antibodies (mAbs) is eligible for continuous processing to lower manufacturing costs...review 2021
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Ciullo, A. (author), Kwakkel, J.H. (author), De Bruijn, Karin M. (author), Doorn, N. (author), Klijn, F. (author)Flood risk management decisions in many countries are based on decision-support frameworks which rely on cost-benefit analyses. Such frameworks are seldom informative about the geographical distribution of risk, raising questions on the fairness of the proposed policies. In the present work, we propose a new decision criterion that accounts...journal article 2020
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Klijn, F. (author), Asselman, Nathalie (author), Mosselman, E. (author), Sperna Weiland, Frederiek (author)Door klimaatverandering verandert het afvoerregime van onze grote rivieren. Hoogwaters worden hoger en frequenter, laagwaters lager en langduriger. Hoe we daarop reageren hangt af van hoe we klimaatverandering zien: als opgave, of als kans om onvolkomenheden aan te pakken. In dit artikel presenteren we aanzetten voor een meer geo-ecologisch...journal article 2019
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Ciullo, A. (author), de Bruijn, Karin M. (author), Kwakkel, J.H. (author), Klijn, F. (author)Most alluvial plains in the world are protected by flood defences, for example, embankments, whose primary aim is to reduce the probability of flooding of the protected areas. At the same time, however, the presence of embankments at one area influences hydraulic conditions of downstream areas located on the same river. These hydraulic...journal article 2019
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Ciullo, A. (author), De Bruijn, Karin M. (author), Kwakkel, J.H. (author), Klijn, F. (author)Rivers typically flow through multiple flood-protected areas which are clearly interconnected, as risk reduction measures taken at one area, e.g. heightening dikes or building flood storage areas, affect risk elsewhere. We call these interconnections 'hydraulic interactions'. The current approach to flood risk management, however, neglects...journal article 2019
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Cumiskey, Lydia (author), Priest, Sally J. (author), Klijn, F. (author), Juntti, Meri (author)Over decades the concept of integration has been promoted to enhance alignment between policy domains, and to manage trade-offs and maximize synergies across management practices. Integrated approaches have the potential to enable better outcomes for flood risk management (FRM) and society as a whole. However, achieving integration in...journal article 2019
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Klijn, F. (author), Asselman, Nathalie (author), Wagenaar, Dennis (author)The Netherlands has just finished implementing the Room for the Rivers program along the Rhine and Meuse Rivers in response to increasing river discharges. Recently, making more room for the river is, however, being challenged for future application because the flood defenses are assessed to be too weak and will need reinforcement anyway. To be...journal article 2018
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Klijn, F. (author), Asselman, Nathalie (author), Mosselman, E. (author)There is increasing attention for the robustness of systems, in view of more frequent and more extreme weather events. Calls to increase a system's robustness are usually motivated by the resulting reduced sensitivity to extreme events and uncertainties about their probability of occurrence. The concept has been elaborated for flood risk systems...journal article 2018
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de Bruijn, Karin (author), Buurman, Joost (author), Mens, Marjolein (author), Dahm, Ruben (author), Klijn, F. (author)The concept of resilience is used by many in different ways: as a scientific concept, as a guiding principle, as inspirational ‘buzzword’, or as a means to become more sustainable. Next to the academic debate on meaning and notions of resilience, the concept has been widely adopted and interpreted in policy contexts, particularly related to...journal article 2017
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De Bruijn, Karin M. (author), Diermanse, Ferdinand L.M. (author), Van Der Doef, Marcel (author), Klijn, F. (author)Knowledge on the different components of flood risk has much improved over the last decades, but research which fully takes into account not only the interactions between those components but also between different areas in a catchment or delta is still rare. Integrated analyses based on a complete system's approach at sufficiently large...journal article 2016
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Asselman, Nathalie E.M. (author), Klijn, F. (author)Since 1996, the Netherlands has adopted a flood risk management policy based on making more room for the rivers. Currently, the focus in flood risk management is being adapted again, in view of increasing societal vulnerability and foreseeable effects of climate change. In this context, the choice between making more room for the river and/or...journal article 2016