Percolate: An Exponential Family JIVE Model to Design DNA-Based Predictors of Drug Response

Motivation: Anti-cancer drugs may elicit resistance or sensitivity through mechanisms which involve several genomic layers. Nevertheless, we have demonstrated that gene expression contains most of the predictive capacity compared to the remaining omic data types. Unfortunately, this comes at a price: gene expression biomarkers are often hard...

EPOS-NL is the Dutch solid earth science infrastructure for research on georesources and geohazards

The European Plate Observing System - Netherlands (EPOS-NL) is the Dutch research infrastructure for solid Earth sciences. EPOS-NL is a cluster of large-scale geophysical facilities for research on georesources and geohazards. It is a partnership between Delft University of Technology (TU Delft), the Royal Netherlands Meteorological Institute...

High-value composite products from fast growing Eucalyptus trees

The objectives of the work described in this paper were to develop concept processing pathways for manufacturing high value, green-glued Eucalyptus composite products, review existing research on this topic, and identify critical knowledge gaps that need to be addressed in future research. A review of research showed that structural grading on...

Use of a future maintenance demand indicator for network level asset management decision making

This paper discusses the development and first testing of a valid, reliable, functional and simple indicator, that represents the long term effect of short term decisions. Such an indicator can assist counteracting short term views in network level asset management decision making. Short-termism or myopia may occur in cases where service level...

Continued Learning in Asset Management for the Dutch Transport Network

Asset management aims at improving the overall performance of assetintensive industries by making and executing systematic and highest value decisions about the use and care of assets. To assist organizations to improve their asset management performance, maturity models can be used. In this paper we describe two applications of the...