LifeTime and improving European healthcare through cell-based interceptive medicine

Here we describe the LifeTime Initiative, which aims to track, understand and target human cells during the onset and progression of complex diseases, and to analyse their response to therapy at single-cell resolution. This mission will be implemented through the development, integration and application of single-cell multi-omics and imaging,...

Flood Risks in Sinking Delta Cities: Time for a Reevaluation?

Sea level rise (SLR) and subsidence are expected to increase the risk of flooding and reliance on flood defenses for cities built on deltas. Here, we combine reliability analysis with hydrodynamic modeling to quantify the effect of projected relative SLR on dike failures and flood hazards for Shanghai, one of the most exposed delta cities. We...

Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9)

In this Perspective, owing to an error in the HTML, the surname of author Alejandro López-Tobón of the LifeTime Community Working Groups consortium was indexed as ‘Tobon’ rather than ‘López-Tobón’ and the accents were missing. The HTML version of the original Perspective has been corrected; the PDF and print versions were always correct.

Putting our money where our mouth is: Open Hydrology Done Right in the eWaterCycle II project

Global modeling of tropical cyclone storm surges using high-resolution forecasts

We assess the suitability of ECMWF Integrated Forecasting System (IFS) data for the global modeling of tropical cyclone (TC) storm surges. We extract meteorological forcing from the IFS at a 0.225° horizontal resolution for eight historical TCs and simulate the corresponding surges using the global tide and surge model. Maximum surge heights...

Spatiotemporal patterns of extreme sea levels along the western North-Atlantic coasts

The western North-Atlantic coast experienced major coastal floods in recent years. Coastal floods are primarily composed of tides and storm surges due to tropical (TCs) and extra-tropical cyclones (ETCs). We present a reanalysis from 1988 to 2015 of extreme sea levels that explicitly include TCs for the western North-Atlantic coastline....

Charge carrier dynamics in semiconductor nanocrystals: Dots, rods and sheets

Thesis about the charge carrier dynamics in PbSe and PbS semiconductor nanocrystals. The main goal of the research is to assess their potential as new materials for high-efficiency solar cells. The nanocrystals under investigation consist of PbSe quantum dots (Ch 2), PbSe nanorods (Ch 3 & 4) and PbS nanosheets (Ch 6), and the spectroscopic...

High charge mobility in two-dimensional percolative networks of PbSe quantum dots connected by atomic bonds

Two-dimensional networks of quantum dots connected by atomic bonds have an electronic structure that is distinct from that of arrays of quantum dots coupled by ligand molecules. We prepared atomically coherent two-dimensional percolative networks of PbSe quantum dots connected via atomic bonds. Here, we show that photoexcitation leads to...

Greenelec: Product design linked to recycling

GreenElec aims to significantly improve on the resource efficiency of electronics and electronic products. This is accomplished by close cooperation between manufacturers and recyclers. Design guidelines for improved recycling have been formulated and products (lamps and displays) have been redesigned according to these guidelines. Interestingly...

Highly efficient carrier multiplication in PbS nanosheets

Semiconductor nanocrystals are promising for use in cheap and highly efficient solar cells. A high efficiency can be achieved by carrier multiplication (CM), which yields multiple electron-hole pairs for a single absorbed photon. Lead chalcogenide nanocrystals are of specific interest, since their band gap can be tuned to be optimal to exploit...

ACER: Developing Adaptive Capacity to Extreme events in the Rhine basin

Water managers in the Rhine basin are increasingly confronted with information on the impact of climate change and climate variability on the discharge regime of their river system. The river Rhine has a long history of flooding events that caused casualties and severe damage. The question remains whether measures that are currently implemented...

Landscape Architecture at TU Delft 1973-2011: Ter gelegenheid afscheid Prof. Dr. Clemens Steenbergen

Het is haast onmogelijk om de werkzame jaren van Prof. Dr. Clemens Steenbergen hier op de TU Delft in het kort samen te vatten. Dit is een persoonlijk boek van collega's, medewerkers en studenten ter gelegenheid van zijn afscheid op 15. December 2011.

Position and orientation determination of a maneuvering target based on moving horizon estimation

Aandacht voor veiligheid

Aandacht voor Veiligheid is een haalbaarheidsstudie waarin wordt verkend welke informatie en methoden beschikbaar zijn om ontwikkelingen op het gebied van waterveiligheid in Nederland op de lange termijn te bestuderen. De studie heeft als opdracht meegekregen om de bandbreedten te verkennen in zowel mogelijke toekomstscenarios als ook de...

Effecten van suppletiezand op verstuiving: Verschillen tussen gesuppleerde en niet-gesuppleerde stranden: Fase 3: Integratiefase

Het huidige kustbeleid is erop gericht de kustlijn van 1990 "dynamisch" te handhaven. Als onderdeel hiervan worden regelmatig zandsuppleties uitgevoerd langs de kust. Met dit project wil de TAW en RWS, door het uitvoeren van gerichte metingen, inzicht krijgen in de verstuiving van suppleties waarbij de gebruiksfunctie recreatie centraal staat....