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Wolfkamp, Wouter (author), Meijer, Joyce (author), van Hoeve, Jolanda C. (author), van Erning, Felice (author), de Geus-Oei, L.F. (author), de Hingh, Ignace (author), Veltman, Jeroen (author), Siesling, Sabine (author)Background: In the Netherlands, the COVID-19 pandemic resulted in a temporary halt of population screening for cancer and limited hospital capacity for non-COVID care. We aimed to investigate the impact of the pandemic on the in-hospital diagnostic pathway of breast cancer (BC) and colorectal cancer (CRC). Methods: 71,159 BC and 48,900 CRC...journal article 2024
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Hendriks, P. (author), Rietbergen, Daphne D.D. (author), van Erkel, Arian R. (author), Coenraad, Minneke J. (author), Arntz, Mark J. (author), Bennink, Roel J. (author), Braat, Andries E. (author), de Geus-Oei, L.F. (author), Burgmans, M.C. (author)Purpose: The aim of this study was to investigate the biodistribution of (super-)selective trans-arterial radioembolization (TARE) with holmium-166 microspheres (<sup>166</sup>Ho-MS), when administered as adjuvant therapy after RFA of HCC 2–5 cm. The objective was to establish a treatment volume absorbed dose that results in an absorbed dose...journal article 2024
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van de Burgt, Alina (author), van Velden, Floris H.P. (author), Kwakkenbos, Koen (author), Smit, Frits (author), de Geus-Oei, L.F. (author), Dekkers, Ilona A. (author)Purpose: Assessing renal perfusion in-vivo is challenging and quantitative information regarding renal hemodynamics is hardly incorporated in medical decision-making while abnormal renal hemodynamics might play a crucial role in the onset and progression of renal disease. Combining physiological stimuli with rubidium-82 positron emission...journal article 2024
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Vuijk, Floris A. (author), Feshtali Shahbazi, Shirin (author), Noortman, W.A. (author), van Velden, Floris H.P. (author), Dibbets-Schneider, Petra (author), Marinelli, Andreas W.K.S. (author), Putter, H. (author), Vahrmeijer, Alexander L. (author), de Geus-Oei, L.F. (author)OBJECTIVE: In this pilot study, we investigated the feasibility of response prediction using digital [ 18 F]FDG PET/computed tomography (CT) and multiparametric MRI before, during, and after neoadjuvant chemoradiation therapy in locally advanced rectal cancer (LARC) patients and aimed to select the most promising imaging modalities and...journal article 2023
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- Slart, Riemer H.J.A. (author), de Geus-Oei, L.F. (author), Stevens, Jasper (author), Elsinga, Philip A. (author), Ivashchenko, O. (author), Erba, Paola A. (author) journal article 2023
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Kleiburg, Fleur (author), Heijmen, Linda (author), Gelderblom, Hans (author), Kielbasa, Szymon M. (author), Bovée, Judith Vmg (author), de Geus-Oei, L.F. (author)Bone and soft tissue sarcomas are a group of rare malignant tumours with major histological and anatomical varieties. In a metastatic setting, sarcomas have a poor prognosis due to limited response rates to chemotherapy. Radioligand therapy targeting prostate-specific membrane antigen (PSMA) may offer a new perspective. PSMA is a type II...review 2023
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- de Koster, Elizabeth J. (author), de Geus-Oei, L.F. (author), Oyen, Wim J.G. (author), Vriens, Dennis (author) journal article 2023
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Linders, D. G.J. (author), Deken, M. M. (author), van Dam, M. A. (author), Wasser, M. N.J.M. (author), Voormolen, E. M.C. (author), Kroep, J. R. (author), van Dongen, G. A.M.S. (author), Vugts, D. (author), de Geus-Oei, L.F. (author)Background: Approximately 20% of invasive ductal breast malignancies are human epidermal growth factor receptor 2 (HER2)-positive. These patients receive neoadjuvant systemic therapy (NAT) including HER2-targeting therapies. Up to 65% of patients achieve a pathological complete response (pCR). These patients might not have needed surgery....journal article 2023
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Chen, Linda L. (author), van de Burgt, Alina (author), Smit, Frits (author), Audhoe, Rowena S. (author), de Boer, Sandra M. (author), van Velden, Floris H.P. (author), de Geus-Oei, L.F. (author)Objective Since the end of 2019, the coronavirus disease 2019 (COVID-19) virus has infected millions of people, of whom a significant group suffers from sequelae from COVID-19, termed long COVID. As more and more patients emerge with long COVID who have symptoms of fatigue, myalgia and joint pain, we must examine potential biomarkers to find...journal article 2023
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Arntz, Pieter J.W. (author), Deroose, Christophe M. (author), Marcus, Charles (author), Sturesson, Christian (author), Panaro, Fabrizio (author), Erdmann, Joris (author), Manevska, Nevena (author), Moadel, Renee (author), de Geus-Oei, L.F. (author)Purpose: The aim of this joint EANM/SNMMI/IHPBA procedure guideline is to provide general information and specific recommendations and considerations on the use of [<sup>99m</sup>Tc]Tc-mebrofenin hepatobiliary scintigraphy (HBS) in the quantitative assessment and risk analysis before surgical intervention, selective internal radiation therapy...journal article 2023
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Vaz, Sofia C. (author), Oliveira, Carla (author), Teixeira, Ricardo (author), Arias-Bouda, Lenka M.Pereira (author), Cardoso, Maria João (author), de Geus-Oei, L.F. (author)Breast cancer is the most common cancer in females worldwide. Nuclear medicine plays an important role in patient management, not only in initial staging, but also during follow-up. Radiopharmaceuticals to study breast cancer have been used for over 50 years, and several of these are still used in clinical practice, according to the most...review 2023
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Pasquier, David (author), Bidaut, Luc (author), Oprea-Lager, Daniela Elena (author), deSouza, Nandita M. (author), Krug, David (author), Collette, Laurence (author), Kunz, Wolfgang (author), Belkacemi, Yazid (author), de Geus-Oei, L.F. (author)Breast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic disease and clinical trials of oligometastatic breast cancer. After an exhaustive review of the literature covering all...review 2023
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Hendriks, P. (author), van Dijk, Kiki M. (author), Boekestijn, Bas (author), Broersen, Alexander (author), van Duijn-de Vreugd, Jacoba J. (author), Coenraad, Minneke J. (author), Dijkstra, J. (author), de Geus-Oei, L.F. (author), Burgmans, M.C. (author)Purpose: The primary objective of this study was to determine the feasibility of ablation margin quantification using a standardized scanning protocol during thermal ablation (TA) of hepatocellular carcinoma (HCC), and a rigid registration algorithm. Secondary objectives were to determine the inter- and intra-observer variability of tumor...journal article 2023
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- Ambrosini, Valentina (author), Carrilho Vaz, Sofia (author), Ahmadi Bidakhvidi, Niloefar (author), Cysouw, Matthijs C.F. (author), Serani, Francesca (author), Deroose, Christophe M. (author), de Geus-Oei, L.F. (author), Konijnenberg, Mark W. (author), Oprea Lager, Daniela E. (author) contribution to periodical 2023
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- Vriens, Dennis (author), de Koster, Elizabeth J. (author), de Geus-Oei, L.F. (author), Oyen, Wim J.G. (author) journal article 2023
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Kalisvaart, Gijsbert M. (author), van Velden, Floris H.P. (author), Hernández-Girón, Irene (author), Meijer, Karin M. (author), Ghesquiere-Dierickx, Laura M.H. (author), Brink, Wyger M. (author), Webb, A. (author), de Geus-Oei, Lioe-Fee (author), Slump, Cornelis H. (author), Kuznetsov, D.V. (author), Schaart, D.R. (author), Grootjans, Willem (author)Background: Accuracy and precision assessment in radiomic features is important for the determination of their potential to characterize cancer lesions. In this regard, simulation of different imaging conditions using specialized phantoms is increasingly being investigated. In this study, the design and evaluation of a modular multimodality...journal article 2022
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Hendriks, P. (author), Berkhout, W. E.M. (author), Kaanen, C.I. (author), Sluijter, J.H. (author), Visser, I. J. (author), van den Dobbelsteen, J.J. (author), de Geus-Oei, L. F. (author), Webb, A. (author), Burgmans, M.C. (author)Purpose: To investigate the performance of two microwave ablation (MWA) systems regarding ablation volume, ablation shape and variability. Materials and Methods: In this ex vivo study, the Emprint and Amica MWA systems were used to ablate porcine livers at 4 different settings of time and power (3 and 5 minutes at 60 and 80 Watt). In total,...journal article 2021
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Noortman, Wyanne A. (author), Vriens, Dennis (author), Mooij, C.D.Y. (author), Slump, Cornelis H. (author), Aarntzen, Erik H. (author), van Berkel, Anouk (author), Timmers, Henri J.L.M. (author), Bussink, Johan (author), Meijer, Tineke W.H. (author), de Geus-Oei, Lioe Fee (author), van Velden, Floris H.P. (author)Background: Central necrosis can be detected on [<sup>18</sup>F]FDG PET/CT as a region with little to no tracer uptake. Currently, there is no consensus regarding the inclusion of regions of central necrosis during volume of interest (VOI) delineation for radiomic analysis. The aim of this study was to assess how central necrosis affects...journal article 2021
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Beekman, Marian (author), Schutte, Bianca A.M. (author), van den Akker, E.B. (author), Noordam, Raymond (author), Dibbets-Schneider, Petra (author), de Geus-Oei, Lioe Fee (author), Deelen, Joris (author), Rest, Ondine van de (author), Heemst, Diana van (author)Scope: Abdominal obesity is one of the main modifiable risk factors of age-related cardiometabolic disease. Cardiometabolic disease risk and its associated high abdominal fat mass, cholesterol, and glucose concentrations can be reduced by a healthier lifestyle. Hence, the aim is to understand the relation between lifestyle-induced changes in...journal article 2020