- document
-
Zhang, F. (author), de Ridder, H. (author), Pont, S.C. (author)To better understand the interactions between material perception and light perception, we further developed our material probe MatMix 1.0 into MixIM 1.0, which allows optical mixing of canonical lighting modes. We selected three canonical lighting modes (ambient, focus, and brilliance) and created scenes to represent the three illuminations....journal article 2018
- document
-
Derks, Martijn F.L. (author), Megens, Hendrik-Jan (author), Bosse, Mirte (author), Visscher, Jeroen (author), Peeters, Katrijn (author), Bink, Marco C.A.M. (author), Vereijken, Addie (author), Groß, C. (author), de Ridder, D. (author), Reinders, M.J.T. (author), Groenen, Martien A.M. (author)Background: Deleterious genetic variation can increase in frequency as a result of mutations, genetic drift, and genetic hitchhiking. Although individual effects are often small, the cumulative effect of deleterious genetic variation can impact population fitness substantially. In this study, we examined the genome of commercial purebred chicken...journal article 2018
- document
-
Gritsenko, A. (author), Weingarten-Gabbay, Shira (author), Elias-Kirma, Shani (author), Nir, Ronit (author), de Ridder, D. (author), Segal, Eran (author)Translation of mRNAs through Internal Ribosome Entry Sites (IRESs) has emerged as a prominent mechanism of cellular and viral initiation. It supports cap-independent translation of select cellular genes under normal conditions, and in conditions when cap-dependent translation is inhibited. IRES structure and sequence are believed to be...journal article 2017
- document
- Zhang, F. (author), de Ridder, H. (author), Barla, Pascal (author), Pont, S.C. (author) poster 2017
- document
-
Jansen, R.J. (author), van Egmond, R. (author), de Ridder, H. (author)The role of task prioritization in performance tradeoffs during multi-tasking has received widespread attention. However, little is known on whether people have preferences regarding tasks, and if so, whether these preferences conflict with priority instructions. Three experiments were conducted with a high-speed driving game and an auditory...journal article 2016
- document
-
Taskesen, E. (author), Huisman, S.M.H. (author), Mahfouz, A.M.E.T.A. (author), Krijthe, J.H. (author), de Ridder, J. (author), van de Stolpe, A. (author), van den Akker, E.B. (author), Verhaegh, Wim (author), Reinders, M.J.T. (author)The use of genome-wide data in cancer research, for the identification of groups of patients with similar molecular characteristics, has become a standard approach for applications in therapy-response, prognosis-prediction, and drug-development. To progress in these applications, the trend is to move from single genome-wide measurements in a...journal article 2016
- document
-
Vegt, N.J.H. (author), Visch, V.T. (author), Vermeeren, A.P.O.S. (author), de Ridder, H. (author)Serious gaming is used as a means for improving organizational teamwork, yet little is known about the effect of individual game elements constituting serious games. This paper presents a game design experiment aimed at generating knowledge on designing game elements for teamwork. In previous work, we suggested that interaction- and goal-driven...journal article 2016
- document
-
Gilroy, Kathryn L. (author), Terry, Anne (author), Naseer, Asif (author), de Ridder, J. (author), Allahyar, A. (author), Wang, Weiwei (author), Carpenter, Eric (author), Mason, Andrew (author), Wong, Gane K.S. (author), Cameron, Ewan R. (author), Kilbey, Anna (author), Neil, James C. (author)Retroviruses have been foundational in cancer research since early studies identified protooncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and entails interaction of viral integrase with host BET/bromodomain factors. We report that this integration...journal article 2016
- document
-
Leendertse, W.L. (author), Arts, Jos (author), de Ridder, H.A.J. (author)The construction industry is going through hard times in many countries. This is certainly true in the Netherlands as all big Dutch contractors face disappointing results. The market policies of major (public) clients are held accountable by politics and the market for this situation. However, for the operation and development of transport...journal article 2016
- document
-
van Bemmelen, C. W T (author), Mann, M. (author), de Ridder, M.P. (author), Rutten, M.M. (author), van de Giesen, N.C. (author)Quantification of human impact on water, sediment, and nutrient fluxes at the global scale demands characterization of reservoirs with an accuracy that is presently unavailable. This letter presents a new method, based on virtual dam placement, to make accurate estimations of area-volume relationships of large reservoirs, using solely readily...journal article 2016
- document
-
Kartashova, T. (author), Sekulovski, D (author), de Ridder, H. (author), te Pas, SF (author), Pont, S.C. (author)Human observers have been demonstrated to be sensitive to the local (physical) light field, or more<br/>precisely, to the primary direction, intensity, and diffuseness of the light at a point in a space. In the<br/>present study we focused on the question of whether it is possible to reconstruct the global visual light field, based on observers’...journal article 2016
- document
-
Zhang, F. (author), de Ridder, H. (author), Fleming, Ronald W. (author), Pont, S.C. (author)MatMix 1.0 is a novel material probe we developed for quantitatively measuring visual perception of materials. We implemented optical mixing of four canonical scattering modes, represented by photographs, as the basis of the probe. In order to account for a wide range of materials, velvety and glittery (asperity and mesofacet scattering) were...journal article 2016
- document
-
de Ridder, Sjoerd (author), van der Neut, J.R. (author), Curtis, A (author), Wapenaar, C.P.A. (author)Recently, a novel method to redatum the wavefield in the sub-surface from a reflection response measured at the surface has gained interest for imaging primaries in the presence of strong internal multiples. A prerequisite for the algorithm is an accurate and correct estimate of the direct-wave Green's function. However, usually we use an...conference paper 2016
- document
-
Li, J. (author), de Ridder, H. (author), Vermeeren, A.P.O.S. (author), Conrado, C. (author), Martella, C. (author)This paper introduces the concept of crowd well-being and the needs for sustaining it. Crowd well-being can be interpreted as crowd members’ evaluations on their emotional reactions, moods and judgments they form about their satisfactions, goals or needs fulfillment in a crowded situation according to the definition of subjective well-being by...conference paper 2013
- document
-
Demirel, H.C. (author), de Ridder, H.A.J. (author), Hertogh, M.J.C.M. (author)Infrastructure road network is a complex system in a fast changing complicated environment and therefore subject to change. The changes refer to demands, requirements, regulations and financial possibilities as well as advanced technologies. Therefore outsourcing maintenance activities are rather difficult. In result, increasing complexity and...conference paper 2013
- document
-
van den Berg, B.A. (author), Thornton, JM (author), Reinders, M.J.T. (author), de Ridder, D. (author), Beer, TAP (author)Our aim is to prioritize human missense mutations by their probability of being disease causing. Such a computational method could be used to obtain a reduced set of mutations with a relatively large fraction of disease related mutations, thereby aiding in the search for this type of mutation within a large mutation set.<br/><br/>Whereas a range...poster 2013
- document
- de Ridder, J. (author), Bromberg, Y (author), Michaut, M (author), Satagopam, VP (author), Corpas, M (author), Macintyre, G (author), Alexandrov, T (author) journal article 2013
- document
-
Babaei, S. (author), Hulsman, M. (author), Reinders, M.J.T. (author), de Ridder, J. (author)We introduce a multi-scale kernel diffusion framework and apply it to a large collection of murine retroviral insertional mutagenesis data. The diffusion strength plays the role of scale parameter. As a result, in addition to detecting genes with frequent mutations in their genomic vicinity (red nodes in the interaction graph) we can also find...poster 2012
- document
- van den Berg, B.A. (author), Reinders, M.J.T. (author), Pel, HJ (author), Roubos, J.A. (author), de Ridder, D. (author) poster 2012
- document
-
van den Berg, B.A. (author), Reinders, M.J.T. (author), Pel, HJ (author), Wu, L (author), Roubos, J.A. (author), de Ridder, D. (author)Aspergillus niger is widely used for industrial enzyme production. Knowledge on high-level protein secretion could be useful to improve production rates. We used sequencebased classification methods to identify important properties<br/>for successful high-level secretion, which will be used to redesign proteins for improved secretion.poster 2011