A patient-specific visualization tool for comprehensive analysis of coronary CTA and perfusion MRI data

Cardiac magnetic resonance perfusion imaging (CMR) and computed tomography angiography (CTA) are widely used to assess heart disease. CMR is used to measure the global and regional myocardial function and to evaluate the presence of ischemia; CTA is used for diagnosing coronary artery disease, such as coronary stenoses. Nowadays, the hemodynamic...

Correspondence free 3D statistical shape model fitting to sparse X-ray projections

Atlas-driven scan planning for high-resolution Micro-SPECT data acquisition based on multi-view photographs: A pilot study

Highly focused Micro-SPECT scanners enable the acquisition of functional small animal data with very high-resolution. To acquire a maximum of emitted photons from a specific structure of interest and at the same time minimize the required acquisition time, typically only a small subvolume of the animal is scanned that contains the organs of...

Atlas-driven scan planning for high-resolution micro-SPECT data acquisition based on multi-vew photographs: A pilot study

Highly focused Micro-SPECT scanners enable the acquisition of functional small animal data with very high-resolution. To acquire a maximum of emitted photons from a specific structure of interest and at the same time minimize the required acquisition time, typically only a small subvolume of the animal is scanned that contains the organs of...

Automated determination of optimal angiographic viewing angles for coronary artery bifurcations from CTA data

For optimal diagnosis and treatment of lesions at coronary artery bifurcations using x-ray angiography, it is of utmost importance to determine proper angiographic viewing angles. Due to the increasing use of CTA as a first line diagnostic tool, 3D CTA data is more frequently available before x-ray angiographic procedures take place. Motivated...

Segmentation of myocardial perfusion MR sequences with multi-band Active Appearance Models driven by spatial and temporal features

This work investigates knowledge driven segmentation of cardiac MR perfusion sequences. We build upon previous work on multi-band AAMs to integrate into the segmentation both spatial priors about myocardial shape as well as temporal priors about characteristic perfusion patterns. Different temporal and spatial features are developed without a...

Labeling the pulmonary arterial tree in CT images for automatic quantification of pulmonary embolism

Contrast-enhanced CT Angiography has become an accepted diagnostic tool for detecting Pulmonary Embolism (PE). The CT obstruction index proposed by Qanadli, which is based on the number of obstructed arterial segments, enables the quantification of PE severity. Because the required manual identification of twenty arterial segments is time...

Integrated visualization of multi-angle bioluminescence imaging and micro CT

This paper explores new methods to visualize and fuse multi-2D bioluminescence imaging (BLI) data with structural imaging modalities such as micro CT and MR. A geometric, back-projection-based 3D reconstruction for superficial lesions from multi-2D BLI data is presented, enabling a coarse estimate of the 3D source envelopes from the multi-2D BLI...