Reconstitution of cytolinker-mediated crosstalk between actin and vimentin

Cell shape and motility are determined by the cytoskeleton, an interpenetrating network of actin filaments, microtubules, and intermediate filaments. The biophysical properties of each filament type individually have been studied extensively by cell-free reconstitution. By contrast, the interactions between the three cytoskeletal networks are...

Do people act differently while using ridesharing services with children?

Children are one of the most vulnerable population groups in traffic crashes. Child safety seats (CSSs) can reduce the severity of crash outcomes for children. The use of CSSs has significantly increased in the U.S. over the last 40 years, but the use of CSSs in popular ridesharing services (RSSs), such as Uber and Lyft, is not widespread. This...

Cross-Version Software Defect Prediction Considering Concept Drift and Chronological Splitting

Concept drift (CD) refers to a phenomenon where the data distribution within datasets changes over time, and this can have adverse effects on the performance of prediction models in software engineering (SE), including those used for tasks like cost estimation and defect prediction. Detecting CD in SE datasets is difficult, but important,...