A Note on Integrity: ILP Modelling and Analysis on Graph Families

This thesis provides a fresh perspective on the (vertex) integrity of graphs, serving as a measure of network robustness. The study begins by introducing fundamental concepts and methods for evaluating the integrity of different graph families. An Integer Linear Programming (ILP) model, specifically designed for assessing integrity, is then...

Magnetoencephalography to characterize cortical effects of conditioned pain modulation in patients treated with spinal cord stimulation

<b>Introduction</b>: Spinal Cord Stimulation (SCS) is a successful last-resort treatment for chronic pain patients, although its exact mechanisms of action (MOAs) still need to be unraveled. The MOAs of SCS partly rely on spinal mechanisms (gate control theory) and supraspinal mechanisms likely play a role as well. Pain processing involves a...

The Palace of Justice in Arnhem as energetic catalyst in its surroundings

The built environment is a major consumer of energy in which many improvement steps have to be made. This project investigates how energy can be more efficient by reducing, reusing and producing energy on an urban and building scale. The research showed that the implementation of a sustainable collective heating system around the Palace of...

Designing a Robust Supply Chain for Military operations: A Multi-Agent Simulation approach considering Platooning

Supply chains are to be found in almost every corporation around the world. When tryingto manage a supply chain often two types of disturbance can jeopardize the effectiveness of a supply chain. These are supply and demand uncertainty. This thesis tries to investigate the effects of those two types of disturbances in a supply chain and seeks to...

Evaluating the usefulness of including flexibility in public transport network design and planning

Investing in urban transit is necessary to fuel urban growth and sustainable mobility. Decision making for public transport projects usually involves long term forecasts of travel demand. Future development of factors that influence those forecasts and hence the expected net societal benefits of the investments are uncertain. Decision makers may...

Endothelial Cell Migration on Fibers Mimicking The Early Fracture Environment

Bone is a tissue with many important functions, such as structural support, organ protection and mineral homeostasis. Additionally, after trauma, it can naturally regenerate into fresh, fully functional bone tissue. However, several factors can significantly impede the healing process and cause the formation of non-union tissue. Costs for...

Reduction of the outflow velocity of a closed fallpipe system: The concept selection and analysis of an outflow velocity reduction mechanism

Subsea rock installation is widely applied in the offshore industry and utilized for a wide range of purposes including but not limited to: pipeline protection, scour protection, insulation of pipelines, upheaval buckling prevention and seabed preparation. Tideway Offshore Solutions is specialized in subsea rock installation and currently...

Increasing speed limit compliance in motorway work zones: A human system integration approach

Speeding in motorway work zones lowers the perceived safety of road workers and increases the accident risks of traffic participants. In a work zone, traffic participants share the road with road workers. Road workers are often vulnerable and feel threatened by vehicles passing with high speed. Traffic participants are also at risk since driving...

Towards better decision support during planned maintenance in the Oxygen Steel Factory 2: An analysis of the effects of maintenance on steel ladle routing

Tata Steel IJmuiden (Tata Steel) is the successor of Koninklijke Nederlandsche Hoogovens en Staalfabrieken NV. Tata Steel is now part of Tata Steel Group, Indias largest industrial group producing in excess of 20 million tons of crude steel annually. Tata Steel produces seven million tons of high quality coated steel per annum. In chapter 1 the...

Rethinking the Spatial Impact of the Olympics

The amount and size of the Olympic facilities have outgrown the needs of host cities. Most Olympic venues cannot be used after the event and maintenance is extremely expensive. Therefore cities cannot optimally benefit from the catalysing effect that mega-events, such as the Olympics, can have on host cities. An over-production of sport venues...

Prognostic Molecular Classification of Breast Cancer Based on Features Extracted from a Scale Space

Breast cancer is one of the most prevalent cancers affecting females in the world. In recent years, many cancer researchers have been trying to determine molecular prognosis tools that predict cancer patient treatment response and/or chance of survival. In particular, the determination of gene expression signatures obtained by feature selection...

Measuring Innovation and the Propensity to Patent

Patents are often taken as an indicator to measure innovativeness, because they are a lot easier to obtain than most others. There is a complication though, which is that patents are not a direct measure of innovativeness: the fit between patents and innovativeness is biased by differing propensities to patent. The propensity to patent was...

Hydrodynamic modelling of roughness discontinuities

In this study the effect of a roughness discontinuity caused by a pipeline cover layer in the sea bed is investigated. As a result of this non-uniform flow configuration, the environmental forces acting on the pipeline cover layer change. To investigate the effect of roughness discontinuities, a numerical model of the flow is made; thereby...