Human Mesenchymal Stem Cell Behaviour on Meso-Scale Substrate Curvature: A Finite Element Analysis of the Effects of Substrate Curvature on Cellular Traction Forces and Morphology

That mechanical properties of the extracellular environment can influence cell behaviour has already been established. Recent studies indicate that human mesenchymal stem cells are affected by the surface curvature of the underlying substrate. However, how meso-scale substrate curvature affects cell behaviour is still not clear. This study...