Medici, M. (author), Arfan Ikram, M. (author), Van der Lijn, F. (author), Den Heijer, T. (author), Vernooij, M.W. (author), Hofman, A. (author), Niessen, W.J. (author), Visser, T.J. (author), Breteler, M.M.B. (author), Peeters, R.P. (author) Background: Thyroid disorders are associated with an increased risk of cognitive impairment and Alzheimer's disease. Both small vessel disease and neurodegeneration have a role in the pathogenesis of cognitive impairment and Alzheimer's disease. Thyroid hormone receptor alpha (TR?) is the predominant TR in brain. The circadian clock gene REV-ERB...
journal article 2012
