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Meijer, D.H.M. (author), Pereira Frias, C.S. (author), Beugelink, J. Wouter (author), Deurloo, Y.N. (author), Janssen, Bert J.C. (author)Establishment of correct synaptic connections is a crucial step during neural circuitry formation. The Teneurin family of neuronal transmembrane proteins promotes cell–cell adhesion via homophilic and heterophilic interactions, and is required for synaptic partner matching in the visual and hippocampal systems in vertebrates. It remains...journal article 2022
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Chataigner, Lucas M.P. (author), Gogou, C. (author), den Boer, Maurits A. (author), Pereira Frias, C.S. (author), Thies-Weesie, Dominique M.E. (author), Granneman, Joke C.M. (author), Heck, Albert J.R. (author), Meijer, D.H.M. (author), Janssen, Bert J.C. (author)Cell-surface expressed contactin 1 and neurofascin 155 control wiring of the nervous system and interact across cells to form and maintain paranodal myelin-axon junctions. The molecular mechanism of contactin 1 – neurofascin 155 adhesion complex formation is unresolved. Crystallographic structures of complexed and individual contactin 1 and...journal article 2022