Full-length single-molecule protein fingerprinting

Proteins are the primary functional actors of the cell. While proteoform diversity is known to be highly biologically relevant, current protein analysis methods are of limited use for distinguishing proteoforms. Mass spectrometric methods, in particular, often provide only ambiguous information on post-translational modification sites, and...

The 2023 terahertz science and technology roadmap

Terahertz (THz) radiation encompasses a wide spectral range within the electromagnetic spectrum that extends from microwaves to the far infrared (100 GHz-∼30 THz). Within its frequency boundaries exist a broad variety of scientific disciplines that have presented, and continue to present, technical challenges to researchers. During the past...

Enhancing Explainability of Automated Vehicles with Culturally-Aware HMIs

In the future, automated vehicles can allow much longer journeys to be undertaken without a driver. This could involve travel across countries with different road systems, traffic rules, and regulations. Disparate cultures also have different expectations of how vehicles should behave. These need to be taken into account when designing HMIs...

Transparent silicon carbide/tunnel SiO₂ passivation for c-Si solar cell front side: Enabling J_sc > 42 mA/cm² and iV_oc of 742 mV

N-type microcrystalline silicon carbide (μc-SiC:H(n)) is a wide bandgap material that is very promising for the use on the front side of crystalline silicon (c-Si) solar cells. It offers a high optical transparency and a suitable refractive index that reduces parasitic absorption and reflection losses, respectively. In this work, we...

Investigation on band segregate formation during the electroslag remelting of H13 die steel

Band segregation has been found in the H13 die steel produced by the electroslag remelting (ESR) technology. Chemical and metallographic studies have been carried out on a one ton ESR ingot of H13 die steel, so as to understand the formation mechanism of the band segregation. The results indicate that the T.O content and S content decreased...

TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms

Terminal uridylyl transferases (TUTs) function as integral regulators of microRNA (miRNA) biogenesis. Using biochemistry, single-molecule, and deep sequencing techniques, we here investigate the mechanism by which human TUT7 (also known as ZCCHC6) recognizes and uridylates precursor miRNAs (pre-miRNAs) in the absence of Lin28. We find that the...

A Review of 3D Cadastre Pilot Project and the Policy of 3D NSDI in the Republic of Korea

Recently, due to rapid urbanization, industrialization and population growth, the structures of cities are changing rapidly; multi-purpose three dimensional facilities above and below surface have been increased. Despite the three dimensional space registration such as building and basement facilities is necessary, it is impossible to represent...

Evidence against a charge density wave on Bi(111)