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van Mierlo, M. (author), Vlutters, M. (author), van Asseldonk, E. H.F. (author), van der Kooij, H. (author)Spatiotemporal gait characteristics change during very slow walking, a relevant speed considering individuals with movement disorders or using assistive devices. However, we lack insights in how very slow walking affects human balance control. Therefore, we aimed to identify how healthy individuals use balance strategies while walking very...journal article 2023
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van Mierlo, M. (author), Abma, M. (author), Vlutters, M. (author), van Asseldonk, E. H.F. (author), van der Kooij, H. (author)Humans prioritize regulation of the whole-body angular momentum (WBAM) during walking. When perturbed, modulations of the moment arm of the ground reaction force (GRF) with respect to the centre of mass (CoM) assist in recovering WBAM. For sagittal-plane perturbations of the WBAM given at toe off right (TOR), horizontal GRF modulations and...journal article 2023
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Waterval, N.F.J. (author), Brehm, M. A. (author), Harlaar, J. (author), Nollet, F. (author)Background: In individuals with unilateral plantar flexor weakness, the second peak of the vertical ground reaction force (GRF) is decreased. This leads to a higher ground reaction force, e.g. impact, of the contralateral leg, potentially explaining quadriceps muscle and/or knee joint pain. Energy cost optimized dorsal leaf ankle-foot...journal article 2022
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van Mierlo, M. (author), Ambrosius, J. I. (author), Vlutters, M. (author), van Asseldonk, E. H.F. (author), van der Kooij, H. (author)Healthy individuals highly regulate their whole body angular momentum (WBAM) during walking. Since WBAM regulation is essential in maintaining balance, a better understanding is required on how healthy individuals recover from WBAM perturbations. We therefore studied how healthy individuals recover WBAM in the sagittal plane. WBAM can be...journal article 2022
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Bayón, Cristina (author), Keemink, Arvid Q.L. (author), van Mierlo, Michelle (author), Rampeltshammer, Wolfgang (author), van der Kooij, H. (author), van Asseldonk, Edwin H.F. (author)BACKGROUND: In the last two decades, lower-limb exoskeletons have been developed to assist human standing and locomotion. One of the ongoing challenges is the cooperation between the exoskeleton balance support and the wearer control. Here we present a cooperative ankle-exoskeleton control strategy to assist in balance recovery after...journal article 2022
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Meinders, Evy (author), Booij, Marjolein J. (author), van den Noort, Josien C. (author), Harlaar, J. (author)Background: Walking speed is a confounding factor in biomechanical analyses of gait, but still many studies compare gait biomechanics at comfortable walking speed (CWS) that is likely to differ between groups or conditions. To identify gait deviation unrelated to walking speed, methods are needed to correct biomechanical data over the gait...journal article 2021
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Flux, Eline (author), van der Krogt, Marjolein M. (author), Harlaar, J. (author), Buizer, Annemieke I. (author), Sloot, Lizeth H. (author)Background: As hyperactive muscle stretch reflexes hinder movement in patients with central nervous system disorders, they are a common target of treatment. To improve treatment evaluation, hyperactive reflexes should be assessed during activities as walking rather than passively. This study systematically explores the feasibility,...journal article 2021
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Schrijvers, Jim C. (author), van den Noort, Josien C. (author), van der Esch, Martin (author), Harlaar, J. (author)Purpose: To compare the responses in knee joint muscle activation patterns to different perturbations during gait in healthy subjects. Scope: Nine healthy participants were subjected to perturbed walking on a split-belt treadmill. Four perturbation types were applied, each at five intensities. The activations of seven muscles surrounding the...journal article 2021
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Schrijvers, J. C. (author), Rutherford, D. (author), Richards, R. (author), van den Noort, J. C. (author), van der Esch, M. (author), Harlaar, J. (author)Background: Gait analysis has been used for decades to quantify knee function in patients with knee osteoarthritis; however, it is unknown whether and to what extent inter-laboratory differences affect the comparison of gait data between studies. Therefore, the aim of this study was to perform an inter-laboratory comparison of knee...journal article 2021
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Bekius, Annike (author), Zandvoort, Coen S. (author), Kerkman, Jennifer N. (author), van de Pol, Laura A. (author), Jeroen Vermeulen, R. (author), Harlaar, J. (author), Daffertshofer, Andreas (author), Buizer, Annemieke I. (author), Dominici, Nadia (author)Early brain lesions which produce cerebral palsy (CP) may affect the development of walking. It is unclear whether or how neuromuscular control, as evaluated by muscle synergy analysis, differs in young children with CP compared to typically developing (TD) children with the same walking ability, before and after the onset of independent...journal article 2021
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Fricke, Simone S. (author), Smits, Hilde J.G. (author), Bayón, Cristina (author), Buurke, Jaap H. (author), van der Kooij, H. (author), van Asseldonk, Edwin H.F. (author)Background: Recently developed controllers for robot-assisted gait training allow for the adjustment of assistance for specific subtasks (i.e. specific joints and intervals of the gait cycle that are related to common impairments after stroke). However, not much is known about possible interactions between subtasks and a better understanding...journal article 2020
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Waterval, Niels F.J. (author), Brehm, Merel Anne (author), Harlaar, J. (author), Nollet, Frans (author)Objective: To describe the orthotic properties and evaluate the effects of ankle-foot orthoses for calf muscle weakness in persons with non-spastic neuromuscular disorders compared with shoes-only. Design: Cross-sectional study. Subjects: Thirty-four persons who used ankle-foot orthoses for non-spastic calf muscle weakness. Methods: The...journal article 2020
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Meyns, P. (author), Kerkum, Y. L. (author), Brehm, M. A. (author), Becher, J. G. (author), Buizer, A. I. (author), Harlaar, J. (author)In children with cerebral palsy (CP), rigid ventral shell ankle-foot orthoses (vAFOs) are often prescribed to reduce excessive knee flexion in stance and lower the energy cost of walking (ECW). However, how vAFOs affect ECW is a complex issue, as vAFOs may have an impact on lower limb biomechanics, upper body movements, and balance. Besides,...journal article 2020
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Veeger, Thom T.J. (author), van Trigt, B. (author), Hu, Hai (author), Bruijn, Sjoerd M. (author), van Dieën, Jaap H. (author)BACKGROUND: Literature describing differences in motor control between low back pain (LBP) patients and healthy controls is very inconsistent, which may be an indication for the existence of subgroups. Pain-related psychological factors might play a role causing these differences. PURPOSE: To examine the relation between fear of movement and...journal article 2020
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Automatic versus manual tuning of robot-assisted gait training in people with neurological disordersFricke, Simone S. (author), Bayón, Cristina (author), van der Kooij, H. (author), Edwin, Edwin H. (author)Background: In clinical practice, therapists choose the amount of assistance for robot-assisted training. This can result in outcomes that are influenced by subjective decisions and tuning of training parameters can be time-consuming. Therefore, various algorithms to automatically tune the assistance have been developed. However, the...journal article 2020
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Waterval, Niels F.J. (author), Nollet, Frans (author), Harlaar, J. (author), Brehm, Merel Anne (author)BACKGROUND: To improve gait, persons with calf muscle weakness can be provided with a dorsal leaf spring ankle foot orthosis (DLS-AFO). These AFOs can store energy during stance and return this energy during push-off, which, in turn, reduces walking energy cost. Simulations indicate that the effect of the DLS-AFO on walking energy cost and...journal article 2019
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Schrijvers, Jim (author), van den Noort, Josien C. (author), van der Esch, Martin (author), Dekker, Joost (author), Harlaar, J. (author)Background: Instability of the knee joint during gait is frequently reported by patients with knee osteoarthritis or an anterior cruciate ligament rupture. The assessment of instability in clinical practice and clinical research studies mainly relies on self-reporting. Alternatively, parameters measured with gait analysis have been explored...review 2019
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Maggioni, S. (author), Melendez-Calderon, A. (author), van Asseldonk, E. (author), Klamroth-Marganska, V (author), Lünenburger, L. (author), Riener, R (author), van der Kooij, H. (author)The assessment of sensorimotor functions is extremely important to understand the health status of a patient and its change over time. Assessments are necessary to plan and adjust the therapy in order to maximize the chances of individual recovery. Nowadays, however, assessments are seldom used in clinical practice due to administrative...review 2016
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Stijntjes, M. (author), De Craen, Anton J M (author), Van Der Grond, Jeroen (author), Meskers, Carel G M (author), Slagboom, P. Eline (author), Maier, Andrea B. (author)Background: The positive relationship between cognitive and physical performance has been widely established. The influence of brain structure on both domains has been shown as well. Objective: We studied whether the relationship between brain structure and physical performance is independent of cognitive performance. Methods: This was a...journal article 2016