Homeostasis in intestinal organoids at the single cell level

How does the small intestine maintain itself? What mechanism does it use to achieve<br/>homeostasis, and how optimal is this mechanism? We approached these questions<br/>mainly using cell tracking in organoids, for which we developed new cell trackers.<br/>We found that the intestinal crypt uses a surprisingly simple and effective strategy.<br/...

Cell Tracking for Organoids: Lessons From Developmental Biology

Organoids have emerged as powerful model systems to study organ development and regeneration at the cellular level. Recently developed microscopy techniques that track individual cells through space and time hold great promise to elucidate the organizational principles of organs and organoids. Applied extensively in the past decade to embryo...