Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine (Nature, (2020), 587, 7834, (377-386), 10.1038/s41586-020-2715-9)

In this Perspective, owing to an error in the HTML, the surname of author Alejandro López-Tobón of the LifeTime Community Working Groups consortium was indexed as ‘Tobon’ rather than ‘López-Tobón’ and the accents were missing. The HTML version of the original Perspective has been corrected; the PDF and print versions were always correct.

The Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor Cells

Purpose: Variations in the radiosensitivity of tumor cells within and between tumors impact tumor response to radiation, including the dose required to achieve permanent local tumor control. The increased expression of DNA-PKcs, a key component of a major DNA damage repair pathway in tumors treated by radiation, suggests that DNA-PKcs– dependent...

A hybrid silicon-PDMS optofluidic platform for sensing applications

A hybrid silicon-poly(dimethysiloxane) (PDMS) optofluidic platform for lab-on-a-chip applications is proposed. A liquid-core waveguide with a self-aligned solid-core waveguide and a microfluidic device are integrated with a multilayer approach, resulting in a three-dimensional device assembly. The optofluidic layer was fabricated with a hybrid...

Optofluidics: A new tool for sensing

Over the last years optofluidics has emerged as a very promising field. The integration at microscopic level between optics and microfluidics provides a number of unique characteristics that cannot be obtained with solid materials only. This paper briefly reviews the state of the art on optofluidics for sensing applications. We first describe...

Computational analysis of self-pitching propellers performance in open water

Optofluidics: Waveguides and devices

In this work we review recent results of our work on optofluidics. We show that single mode optofluidic waveguides with low loss can be realized using antiresonant reflecting optical confinement (ARROW). These waveguides can be fabricated using full standard silicon technology or hybrid silicon-polymer processes. ARROW waveguides have been used...

Liquid core integrated ring resonator

We report the design and the fabrication of an integrated optofluidic ring resonator based on liquid core antiresonant reflecting optical waveguide (ARROW) operating around ?=635nm with a water filled core (nc=1.33). This waveguide permits a strong coupling between light and analyte as the same microchannel can be used for delivering sample and...

Integrated silicon optofluidic ring resonator

The feasibility of an integrated silicon optofluidic ring resonator is demonstrated. Liquid core antiresonant reflecting optical waveguides are used to realize a rectangular ring resonator with a multimode interference liquid core coupler between the ring and the bus waveguide. In this configuration the same waveguide used to confine the light...

Waveguide based optofluidics

Integrated liquid core AntiResonant Reflecting Optical Waveguide (ARROW) are used as basic component for the realization of complex optofluidic devices. Liquid core ARROW waveguides permit to confine the light in a low refractive index liquid core, by means of two high refractive index cladding layers designed to form a high reflectivity Fabry...

Acoustic formulations for aeronautical and naval rotorcraft noise prediction based on the Ffowcs Williams and Hawkings equation