- document
-
Ferrao Blanco, M. N. (author), Domenech Garcia, H. (author), Legeai-Mallet, L. (author), van Osch, G.J.V.M. (author)Osteoarthritis (OA) is a major health problem worldwide that affects the joints and causes severe disability. It is characterized by pain and low-grade inflammation. However, the exact pathogenesis remains unknown and the therapeutic options are limited. In OA articular chondrocytes undergo a phenotypic transition becoming hypertrophic, which...review 2021