Asymmetric α-benzylation of cyclic ketones enabled by concurrent chemical aldol condensation and biocatalytic reduction

Chemoenzymatic cascade catalysis has emerged as a revolutionary tool for streamlining traditional retrosynthetic disconnections, creating new possibilities for the asymmetric synthesis of valuable chiral compounds. Here we construct a one-pot concurrent chemoenzymatic cascade by integrating organobismuth-catalyzed aldol condensation with ene...

A Low-Spur Fractional-N PLL Based on a Time-Mode Arithmetic Unit

This article introduces a low-jitter low-spur fractional-N phase-locked loop (PLL) adopting a new concept of a time-mode arithmetic unit (TAU) for phase error extraction. The TAU is a time-signal processor that calculates the weighted sum of input time offsets. It processes two inputs - the period of a digitally controlled oscillator (DCO)...

Bilevel Model for Protection-Branch Measurements-Based Topology Attack Against DC and AC State Estimations

A topology attack, as a special class of false data injection attacks, tampers with topology information of a system to mislead the decision of the control center. This article conducts an in-depth study on topology attacks that aim to interfere with the judgment in topology information and pose potential damage by tampering with measurement...

Unified Binary Generative Adversarial Network for Image Retrieval and Compression

Binary codes have often been deployed to facilitate large-scale retrieval tasks, but not that often for image compression. In this paper, we propose a unified framework, BGAN+, that restricts the input noise variable of generative adversarial networks to be binary and conditioned on the features of each input image, and simultaneously learns...

Double helical conformation and extreme rigidity in a rodlike polyelectrolyte

The ubiquitous biomacromolecule DNA has an axial rigidity persistence length of ~50 nm, driven by its elegant double helical structure. While double and multiple helix structures appear widely in nature, only rarely are these found in synthetic non-chiral macromolecules. Here we report a double helical conformation in the densely charged...

Is “Morphodynamic Equilibrium” an oxymoron?

Morphodynamic equilibrium is a widely adopted yet elusive concept in the field of geomorphology of coasts, rivers and estuaries. Based on the Exner equation, an expression of mass conservation of sediment, we distinguish three types of equilibrium defined as static and dynamic, of which two different types exist. Other expressions such as...