Enzyme engineering for biocatalysis

Contemporary Biocatalysis heavily relies on enzyme engineering as natural enzymes frequently lack the requisite attributes for effective organic synthesis. The inherent limitations in stability, catalytic activity, and selectivity of wild-type enzymes often hinder their suitability for chemical synthesis. Over the past 25 years, there has...

DaisyRec 2.0: Benchmarking Recommendation for Rigorous Evaluation

Recently, one critical issue looms large in the field of recommender systems - there are no effective benchmarks for rigorous evaluation - which consequently leads to unreproducible evaluation and unfair comparison. We, therefore, conduct studies from the perspectives of practical theory and experiments, aiming at benchmarking recommendation...

Revisiting Bundle Recommendation: Datasets, Tasks, Challenges and Opportunities for Intent-aware Product Bundling

Product bundling is a commonly-used marketing strategy in both offline retailers and online e-commerce systems. Current research on bundle recommendation is limited by: (1) noisy datasets, where bundles are defined by heuristics, e.g., products co-purchased in the same session; and (2) specific tasks, holding unrealistic assumptions, e.g.,...

Joint migration inversion: Features and challenges

Joint migration inversion is a recently proposed technology, accommodating velocity model building and seismic migration in one integrated process. Different from the widely accepted full waveform inversion technology, it uses imaging parameters, i.e. velocities and reflectivities of the subsurface, to parameterize its solution space. The...